1. Metabolic Enzyme/Protease
  2. FABP
  3. LDN-0088050

LDN-0088050 

Cat. No.: HY-100467
Handling Instructions

LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM.

For research use only. We do not sell to patients.

LDN-0088050 Chemical Structure

LDN-0088050 Chemical Structure

CAS No. : 353484-30-7

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Description

LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1].

IC50 & Target

Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]
Kd: 2.05 μM (FABP4)[1]

In Vitro

LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1].

Molecular Weight

372.26

Formula

C₁₉H₁₈BrNO₂

CAS No.

353484-30-7

SMILES

OC(C(C1C2C=CC1)N3CC4C(C=CC4)C5=CC(Br)=CC2=C35)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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LDN-0088050
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