1. Anti-infection
  2. Antibiotic Bacterial
  3. Linopristin

Linopristin is a kind of type B streptogramin antibiotics. Linopristin, together with type A, Flopristin, to form the streptogramin combination NXL 103. Linopristin exhibit synergistic antimicrobial activity against certain pathogenic bacteria with Flopristin. The preference ratio of Linopristin/Flopristin is 30:70 (w/w) or 70 μM Linopristin +120 μM Flopristin.

For research use only. We do not sell to patients.

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Linopristin Chemical Structure

Linopristin Chemical Structure

CAS No. : 325965-23-9

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Description

Linopristin is a kind of type B streptogramin antibiotics. Linopristin, together with type A, Flopristin, to form the streptogramin combination NXL 103. Linopristin exhibit synergistic antimicrobial activity against certain pathogenic bacteria with Flopristin. The preference ratio of Linopristin/Flopristin is 30:70 (w/w) or 70 μM Linopristin +120 μM Flopristin[1].

In Vitro

Linopristin (0-64 μg/mL) has little effect on the the Gram-negative pathogens, due to its poor permeability of the outer cell membrane[1].
Linopristin inhibits the growth of E. faecalis, S. aureus, S. pneumoniae, with IC50s of 8 μM, 32 μM, and 4 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

950.09

Formula

C50H63N9O10

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Linopristin Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Linopristin
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HY-P1705
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