Literature

Aging Without Dying -- The secret of longevity interpreted by high score literature

2022-12-21

Understanding the mechanism of aging not only has guiding significance for prolonging human life but also has important clinical significance for the prevention and treatment of diseases in the elderly population , thus, improving their life quality and well-being.
Efferocytosis: the terminal station for dying cells

2022-12-14

Efferocytosis is the process in which phagocytes remove programmed dead cells. It prevents secondary necrosis of dying cells from releasing harmful cell contents (such as oxides and proteases) that may cause inflammation. Here, we will introduce three stages of efferocytosis: Find, Eat, Digest.
Cell | Transformation of Morphine and Fentanyl!

2022-12-07

As powerful pain relievers, the opioids morphine and fentanyl have been "checked" by their side effects (listed as controlled substances). How to reduce its side effects? What is its mechanism? This research will explore its mechanism.

Exosomes: isolation, labeling and identification

2022-09-01

Exosomes are nano-sized biovesicles released into surrounding body fluids after the fusion of multivesicular bodies with the plasma membrane. In this article, we will briefly introduce isolation, labeling and identification of exosomes. And the specific application of exosomes will also be mentioned.
Cell Apoptosis/Methods for the detection of apoptosis

2022-08-25

Apoptosis is a form of programmed cell death. There are many methods to detect apoptosis which can roughly be divided into three categories: based on cell morphology, biological function and biochemical markers. Some of the most commonly employed assays are described in this article.
ROS Probes-All Eyes Are Focused Here！

2022-08-04

In this article, we will introduce different ROS probes: ROS probe H2DCFDA, •O_2⁻ probes HKSOX-1 and HKSOX-1r, and H₂O₂ probe HKPerox-2. Here we will explains the protocol to use these probes, additionally, some case study for probe usage are listed.

Etrolizumab (rhuMAb Beta7) is a Gut-selective, Anti-β7 Integrin McAb for Inflammatory Bowel Disease (IBD) Research

2022-11-05

Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab decreases β7 integrins of T lymphocytes. Etrolizumab can be used for the research of inflammatory bowel disease.
Pelecopan (BCX9930) is a Selective, Orally Active Complement Factor D Inhibitor

2022-08-20

Pelecopan is a potent, selective, and orally active complement factor D inhibitor, possessing the potential to study paroxysmal nocturnal hemoglobinuria (PNH).
BM213 is a Potent and Selective Agonist of Complement C5a Receptor 1

2022-03-28

BM213 is a selective C5aR1 agonist. It’s a useful research tool to study C5aR1 function

Biomedical Dictionary

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