1. Immunology/Inflammation
  2. CD28
  3. Lulizumab pegol

Lulizumab pegol  (Synonyms: BMS-931699)

Cat. No.: HY-P99717

Lulizumab pegol (BMS-931699) is an anti-CD28 antibody antagonist. Lulizumab pegol effectively inhibits T-cell proliferation and it can be used for the reseach of kidney transplantation and autoimmunity disease.

For research use only. We do not sell to patients.

Lulizumab pegol Chemical Structure

Lulizumab pegol Chemical Structure

CAS No. : 1421830-13-8

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Description

Lulizumab pegol (BMS-931699) is an anti-CD28 antibody antagonist. Lulizumab pegol effectively inhibits T-cell proliferation and it can be used for the reseach of kidney transplantation and autoimmunity disease[1].

In Vitro

BMS-931699 shows a Kd value of 0.41 nM for T-cell proliferation by Biacore[1].
BMS-931699 shows EC50 values of 2.9 and 4.4 nM for T-cell proliferation driven by mixed lymphocyte reaction (MLR) assay and CD28 receptor occupancy (RO) in whole blood[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
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SMILES

[Lulizumab pegol]

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Lulizumab pegol Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lulizumab pegol
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