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Macropa-NH2 

Cat. No.: HY-111895
Handling Instructions

Macropa-NH2 is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases.

For research use only. We do not sell to patients.

Macropa-NH2 Chemical Structure

Macropa-NH2 Chemical Structure

CAS No. : 2146095-13-6

Size Price Stock
5 mg USD 650 Get quote
10 mg USD 950 Get quote
50 mg USD 2950 Get quote
100 mg USD 4950 Get quote

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Other In-stock Forms of Macropa-NH2:

Other Forms of Macropa-NH2:

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Description

Macropa-NH2 is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1][2].

Molecular Weight

547.60

Formula

C₂₆H₃₇N₅O₈

CAS No.

2146095-13-6

SMILES

O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (152.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8262 mL 9.1308 mL 18.2615 mL
5 mM 0.3652 mL 1.8262 mL 3.6523 mL
10 mM 0.1826 mL 0.9131 mL 1.8262 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.80 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.80 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.80 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Macropa-NH2
Cat. No.:
HY-111895
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