1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MC-PBD

MC-PBD 

Cat. No.: HY-136292
Handling Instructions

MC-PBD consists a non-cleavable ADC linker MC and a cytotoxic DNA crosslinking pyrrolobenzodiazepine (PBD). MC-PBD can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

MC-PBD Chemical Structure

MC-PBD Chemical Structure

CAS No. : 1342820-52-3

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Description

MC-PBD consists a non-cleavable ADC linker MC and a cytotoxic DNA crosslinking pyrrolobenzodiazepine (PBD). MC-PBD can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Maytansinoids

 

Molecular Weight

918.99

Formula

C₅₂H₅₀N₆O₁₀

CAS No.

1342820-52-3

SMILES

O=C(N(C=C(C1=CC=C(OC)C=C1)C2)[[email protected]]2([H])C=N3)C4=C3C=C(OCCCOC5=CC6=C(C(N7[[email protected]@]([H])(CC(C8=CC=C(NC(CCCCCN9C(C=CC9=O)=O)=O)C=C8)=C7)C=N6)=O)C=C5OC)C(OC)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MC-PBDDrug-Linker Conjugates for ADCcytotoxicDNAADC?linkerantibody-drug,?conjugateInhibitorinhibitorinhibit

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