1. Cytoskeleton
    Cell Cycle/DNA Damage
    Antibody-drug Conjugate/ADC Related
  2. Microtubule/Tubulin
    Drug-Linker Conjugates for ADC
  3. MC-VC-PAB-MMAD

MC-VC-PAB-MMAD 

Cat. No.: HY-136316
Handling Instructions

MC-VC-PAB-MMAD is a drug-linker conjugate for ADC with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker MC-VC-PAB.

For research use only. We do not sell to patients.

MC-VC-PAB-MMAD Chemical Structure

MC-VC-PAB-MMAD Chemical Structure

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Description

MC-VC-PAB-MMAD is a drug-linker conjugate for ADC with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker MC-VC-PAB[1].

IC50 & Target

Auristatin

 

Molecular Weight

1368.72

Formula

C₇₁H₁₀₅N₁₁O₁₄S

SMILES

O=C(C[[email protected]@H](C(C)C)C(N[[email protected]@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[[email protected]@H](C(C)C)C(N[[email protected]](C(N(C)[[email protected]]([[email protected]@H](CC(N2[[email protected]]([[email protected]@H]([[email protected]](C(N[[email protected]@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)OC)CCC2)=O)OC)[[email protected]@H](C)CC)=O)C(C)C)=O)=O)C=C1)=O)=O)CCCCCN5C(C=CC5=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MC-VC-PAB-MMADMicrotubule/TubulinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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MC-VC-PAB-MMAD
Cat. No.:
HY-136316
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