1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Medetomidine hydrochloride

Medetomidine hydrochloride (Synonyms: MPV785)

Cat. No.: HY-17034B Purity: 99.88%
Handling Instructions

Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.

For research use only. We do not sell to patients.

Medetomidine hydrochloride Chemical Structure

Medetomidine hydrochloride Chemical Structure

CAS No. : 86347-15-1

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10 mM * 1 mL in Water USD 61 In-stock
Estimated Time of Arrival: December 31
10 mg USD 55 In-stock
Estimated Time of Arrival: December 31
50 mg USD 180 In-stock
Estimated Time of Arrival: December 31
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Description

Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. Target: Adrenergic alpha-2 Receptor Medetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Medetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Medetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3].

Molecular Weight

236.74

Formula

C₁₃H₁₇ClN₂

CAS No.

86347-15-1

SMILES

CC(C1=CN=CN1)C2=CC=CC(C)=C2C.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

: ≥ 50 mg/mL (211.20 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2240 mL 21.1202 mL 42.2404 mL
5 mM 0.8448 mL 4.2240 mL 8.4481 mL
10 mM 0.4224 mL 2.1120 mL 4.2240 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

MedetomidineMPV785MPV 785MPV-785Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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Product name:
Medetomidine hydrochloride
Cat. No.:
HY-17034B
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