1. TGF-beta/Smad
  2. TGF-β Receptor
  3. Myostatin-IN-1

Myostatin-IN-1 

Cat. No.: HY-P99005
Handling Instructions

Myostatin-IN-1 is a potent myostatin inhibitor (IC50 of 0.19, 0.63, 0.89 and 1.6 μM for myostatin, GDF-11, activin A and TGF-β1, respectively). Myostatin-IN-1 increases the tibialis anterior muscle mass in mice. Myostatin-IN-1 can be used for researching the prolonged inactivation of myostatin in skeletal muscle.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Myostatin-IN-1 Chemical Structure

Myostatin-IN-1 Chemical Structure

CAS No. : 2757831-08-4

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All TGF-β Receptor Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Myostatin-IN-1 is a potent myostatin inhibitor (IC50 of 0.19, 0.63, 0.89 and 1.6 μM for myostatin, GDF-11, activin A and TGF-β1, respectively). Myostatin-IN-1 increases the tibialis anterior muscle mass in mice. Myostatin-IN-1 can be used for researching the prolonged inactivation of myostatin in skeletal muscle[1].

IC50 & Target

IC50: 0.19 μM (myostatin), 0.63 μM (GDF-11), 0.89 μM (activin A), 1.6 μM (TGF-β1)[1]

In Vitro

Myostatin-IN-1 (MID-35) (50 µM; 400 min) possesses complete proteolytic stability, and can survive 99 and 97% of the intact form incubated for 400 min in trypsin or α-chymotrypsin solution[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Myostatin-IN-1 (0.75 mM; i.m.; single) can significantly induce the increase in tibialis anterior (TA) muscle mass in C57BL/6J mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J mice (8 weeks)[1]
Dosage: 0.75 mM
Administration: i.m.; single
Result: Significantly induced the increase in tibialis anterior (TA) muscle mass in C57BL/6J mice.
Molecular Weight

2350.94

Formula

C118H184N34O17

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Myostatin-IN-1
Cat. No.:
HY-P99005
Quantity:
MCE Japan Authorized Agent: