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  4. Odulimomab

Odulimomab  (Synonyms: anti-LFA1)

Cat. No.: HY-P99765

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Odulimomab (anti-LFA1) is an anti-LFA-1 monoclonal antibody. Odulimomab inhibits proliferation of T lymphocyte and shows protective effects against ischemia and reperfusion injury. Odulimomab can be used for the research of transplant rejection and immunological disease.

For research use only. We do not sell to patients.

Odulimomab Chemical Structure

Odulimomab Chemical Structure

CAS No. : 159445-64-4

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Odulimomab Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

Odulimomab (anti-LFA1) is an anti-LFA-1 monoclonal antibody. Odulimomab inhibits proliferation of T lymphocyte and shows protective effects against ischemia and reperfusion injury. Odulimomab can be used for the research of transplant rejection and immunological disease[1][2].

In Vitro

Odulimomab inhibits proliferation of T lymphocyte, and cytotoxicity and antibody production of T and Natural Killer (NK) cells in vitro[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Odulimomab Related Antibodies
In Vivo

Odulimomab (1.5 and 0.75 mg/kg; i.p., 1.5 mg/kg for the first treatment then followed by daily injection of 0.75 mg/kg until sacrifice) shows protective effects against ischemia and reperfusion injury, and also repairs in renal function after transplantation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cynomolgus Monkeys with renal damage ischemia and kidney autotransplantation[1]
Dosage: 1.5 and 0.75 mg/kg
Administration: Intraperitoneal injection; 1.5 mg/kg for the first dose and after pedicle clamping followed by daily injection of 0.75 mg/kg until sacrifice
Result: Decreased the creatinine level after ischemia and autotransplantation for 3 days and increased the potassium fraction reabsorption.
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[Odulimomab]
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Odulimomab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Odulimomab159445-64-4anti-LFA1IntegrinT lymphocyteNKischemia and reperfusion injuryrenalmonkeyInhibitorinhibitorinhibit

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