1. Autophagy
    Epigenetics
    Cell Cycle/DNA Damage
  2. Autophagy
    Mitophagy
    PARP
  3. Olaparib D4

Olaparib D4 (Synonyms: AZD2281 D4; KU0059436 D4)

Cat. No.: HY-10162S2
Handling Instructions

Olaparib D4 (AZD2281 D4) is the deuterium labeled Olaparib (AZD2281). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator.

For research use only. We do not sell to patients.

Olaparib D4 Chemical Structure

Olaparib D4 Chemical Structure

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Description

Olaparib D4 (AZD2281 D4) is the deuterium labeled Olaparib (AZD2281). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].

Molecular Weight

438.49

Formula

C₂₄H₁₉D₄FN₄O₃

SMILES

O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)C5=C1C([2H])=C([2H])C([2H])=C5[2H]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Olaparib D4AZD2281 D4 KU0059436 D4Olaparib D 4Olaparib D-4AutophagyMitophagyPARPMitochondrial Autophagypoly ADP ribose polymeraseInhibitorinhibitorinhibit

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Olaparib D4
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