1. Antibody-drug Conjugate/ADC Related
    Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC
    DNA Alkylator/Crosslinker
  3. OSu-PEG4-VC-PAB-Duocarmycin SA

OSu-PEG4-VC-PAB-Duocarmycin SA 

Cat. No.: HY-136319
Handling Instructions

SA is a drug-linker conjugate for ADC with potent antitumor activity by using Duocarmycin SA (a potent DNA alkylation activator), linked via the cleavable ADC linker OSu-PEG4-VC-PAB.

For research use only. We do not sell to patients.

OSu-PEG4-VC-PAB-Duocarmycin SA Chemical Structure

OSu-PEG4-VC-PAB-Duocarmycin SA Chemical Structure

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Description

SA is a drug-linker conjugate for ADC with potent antitumor activity by using Duocarmycin SA (a potent DNA alkylation activator), linked via the cleavable ADC linker OSu-PEG4-VC-PAB.

IC50 & Target

Duocarmycins

 

Molecular Weight

1406.88

Formula

C₆₅H₈₄ClN₁₁O₂₂

SMILES

O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)C[[email protected]]3CCl)=CC(OC(N(C)CCN(C)C(OCC(C=C6)=CC=C6NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCOCCOCCOCCOCCC(ON7C(CCC7=O)=O)=O)=O)=O)=O)=O)=O)=C2N1)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

OSu-PEG4-VC-PAB-Duocarmycin SADrug-Linker Conjugates for ADCDNA Alkylator/CrosslinkerInhibitorinhibitorinhibit

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Product name:
OSu-PEG4-VC-PAB-Duocarmycin SA
Cat. No.:
HY-136319
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