1. MAPK/ERK Pathway
  2. p38 MAPK
  3. p38-α MAPK-IN-5

p38-α MAPK-IN-5 

Cat. No.: HY-147518
Handling Instructions

p38-α MAPK-IN-5 (compound 4e) is a potent p38α inhibitor with IC50s of 0.1 nM, 0.2 nM, 944 nM, 4100 nM for p38α, p38 β, p38γ, p38δ, respectively. p38-α MAPK-IN-5 has anti-inflammatory effect. p38-α MAPK-IN-5 has the potential for asthma and chronic obstructive pulmonary disease (COPD) research.

For research use only. We do not sell to patients.

p38-α MAPK-IN-5 Chemical Structure

p38-α MAPK-IN-5 Chemical Structure

CAS No. : 1443242-46-3

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Description

p38-α MAPK-IN-5 (compound 4e) is a potent p38α inhibitor with IC50s of 0.1 nM, 0.2 nM, 944 nM, 4100 nM for p38α, p38 β, p38γ, p38δ, respectively. p38-α MAPK-IN-5 has anti-inflammatory effect. p38-α MAPK-IN-5 has the potential for asthma and chronic obstructive pulmonary disease (COPD) research[1].

IC50 & Target[1]

p38α

0.1 nM (IC50)

p38β

0.2 nM (IC50)

p38γ

944 nM (IC50)

p38δ

4100 nM (IC50)

Molecular Weight

679.86

Formula

C37H49N11O2

CAS No.
SMILES

O=C(N[[email protected]]1CC[[email protected]](C2=C1C=CC=C2)OC(C=C3)=CN4C3=NN=C4N5[[email protected]](CCCC5)C)NC6=CC(C(C)(C)C)=NN6C7=CN(N=C7)CCN(C)C

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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p38-α MAPK-IN-5
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