1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. Thalidomide 4'-ether-alkylC2-amine hydrochloride

Thalidomide 4'-ether-alkylC2-amine hydrochloride 

Cat. No.: HY-136162
Handling Instructions

Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

For research use only. We do not sell to patients.

Thalidomide 4'-ether-alkylC2-amine hydrochloride Chemical Structure

Thalidomide 4'-ether-alkylC2-amine hydrochloride Chemical Structure

CAS No. : 2341840-99-9

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Description

Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC50 & Target[1]

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

353.76

Formula

C15H16ClN3O5

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Thalidomide 4'-ether-alkylC2-amine hydrochloride
Cat. No.:
HY-136162
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