1. Recombinant Proteins
  2. Immune Checkpoint Proteins
  3. Inhibitory checkpoint molecules
  4. B7-H4 & B7-H4R

B7-H4 (also known as B7-S1, B7x and VCTN1), a member of the CD28/B7 family, is a transmembrane protein and a T-cell immune co-inhibitory molecule. B7-H4 negatively regulates T cell immune response and promotes immune escape by inhibiting the proliferation, cytokine secretion, and cell cycle of T cells. B7-H4 is limited expressed in normal peripheral tissues, whereas it is abnormally expressed in inflammation, autoimmune diseases and tumors, such as breast carcinomas. The amino acid sequence of human B7-H4 is highly conserved with approximately 87% amino acid identity to mouse.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7640
    B7-H4 Protein, Human (HEK293, Fc)

    rHuB7-H4, C-Fc; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1

    Human HEK 293
    B7-H4 Protein, Human (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.
  • HY-P72341
    B7-H4 Protein, Human (Biotinylated, HEK 293, Fc-Avi)

    B7S1; B7x; Vtcn1; B7h.5; B7S1VCTN1; B7XPRO1291; FLJ22418; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1

    Human HEK293
  • HY-P74393
    B7-H4 Protein, Mouse (sf9, His)

    V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4

    Mouse Sf9 insect cells
  • HY-P74394
    B7-H4 Protein, Mouse (HEK293, His)

    V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4

    Mouse HEK293
  • HY-P74395
    B7-H4 Protein, Human (HEK293, His)

    V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4

    Human HEK293
  • HY-P75485
    B7-H4 Protein, Rat (HEK293, His)

    V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4

    Rat HEK 293
  • HY-P7641
    B7-H4 Protein, Mouse (HEK293, Fc)

    rMuB7-H4, C-Fc; V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; Protein B7S1; B7-H4;

    Mouse HEK 293
    B7-H4 Protein, Mouse (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.
  • HY-P7642
    B7-H4 Protein, Rhesus macaque (HEK293, His)

    rRhB7-H4, His; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1

    Rhesus Macaque HEK 293
    B7-H4 Protein, Rhesus macaque (HEK293, His) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.
  • HY-P7643
    B7-H4 Protein, Rhesus macaque (HEK293, Fc)

    rRhB7-H4, C-Fc; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1

    Rhesus Macaque HEK 293
    B7-H4 Protein, Rhesus macaque (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.
  • HY-P77543
    TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated)

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1

    Cynomolgus E.coli
Cat. No. Product Name Effect Purity