1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. FGF family
  4. FGF

Fibroblast growth factors (FGFs) are a family of structurally related polypeptide growth factors that have diverse roles in regulating cell proliferation, migration, differentiation, and apoptosis. In vertebrates, the 22 members of the FGF family range in molecular mass from 17 to 34 kDa. They share 13-71% amino acid identity. Most FGFs share an internal core region of similarity, with 28 highly conserved and six identical amino-acid residues. FGFs are highly conserved in both gene structure and amino-acid sequence between vertebrate species. Phylogenetic analysis of the human Fgf gene family can be divided into seven subfamilies: Fgf1/2, Fgf4/5/6, Fgf3/7/10/22, Fgf8/17/18, Fgf9/16/20, Fgf11/12/13/14 and Fgf19/21/23. In addition, the human and mouse FGF families do not include FGF15 or FGF19, respectively, because they are orthologs. By their mechanisms of action, FGFs also can be classified as: 1) Intracrine FGFs, FGF11-FGF14, which regulates the electrical excitability of neurons and possibly other cell types; 2) Paracrine FGFs (FGF/1/2/5, FGF3/4/6, FGF7/10/22, FGF8/17/18 and FGF9/16/20 subfamilies), act on nearby target cells as locally secreted signals via diffusion. Paracrine FGFs bindsto and activates cell surface tyrosine kinase FGFRs with heparin/heparan sulphate as a cofactor; 3) Endocrine FGFs (FGF15/19, FGF21 and FGF23) are thought to mediate their biological responses in an FGFR-dependent manner. Endocrine FGFs has low heparan sulfate-binding affinity and require αKlotho or βKlotho, which are specifically expressed in the target tissues, as a co-factor for FGFR.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7091
    FGF-2 Protein, Rat

    rRtbFGF; HBGF-2; FGF-2; FGF-b; FGF-basic

    Rat E. coli
    FGF-2 Protein, Rat is a growth factor and signaling protein encoded by the FGF2 gene.
  • HY-P7014
    FGF-4 Protein, Human (166a.a)

    rHuFGF-4; HBGF-4; HST; HST-1; HSTF1

    Human E. coli
    FGF-4 Protein, Human (166a.a) is a member of the FGF family that transforms 3T3 cells with high efficiency, stimulates endothelial cell proliferation, migration, and protease production, and shows angiogenic activity.
  • HY-P7004
    FGF basic/bFGF Protein, Human (146a.a)

    rHubFGF; HBGF-2; FGF-2; FGF-b; FGF-basic

    Human E. coli
    FGF basic/bFGF Protein, Human (146a.a) is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts.
  • HY-P70695
    KGF-2/FGF-10 Protein, Human (171a.a)

    Fibroblast growth factor 10; FGF-10; Keratinocyte growth factor 2; FGF10; KGF-2; KGF2

    Human E. coli
  • HY-P7331
    FGF basic/bFGF Protein, Human (154a.a)

    rHubFGF, 154a.a.; bFGF; FGF-2; HBGF-2; FGFB

    Human E. coli
    FGF basic/bFGF Protein, Human (154a.a) is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts, with 154 amino acid.
  • HY-P7048
    KGF-2/FGF-10 Protein, Human (169a.a)

    rHuKGF-2/FGF-10; Fibroblast Growth Factor-10

    Human E. coli
    KGF-2/FGF-10 Protein, Human (159a.a) is a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the growth, proliferation, and differentiation of epithelial cells and can enhance corneal wound healing.
  • HY-P70600
    FGF-2 Protein, Human (K128N)

    Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB

    Human E. coli
  • HY-P7173
    FGF-21 Protein, Mouse

    rMuFGF-21; FGF21

    Mouse E. coli
    FGF-21 Protein, Mouse emerges as a metabolic hormone involved in the regulation of glucose, lipid, bile acid, and phosphate metabolism.
  • HY-P70473
    FGF-21 Protein, Human (His)

    Fibroblast Growth Factor 21; FGF-21; FGF21

    Human E. coli
  • HY-P7330
    FGF basic/bFGF Protein, Human (145a.a)

    rHubFGF, 145a.a.; bFGF; FGF-2; HBGF-2; FGFB

    Human E. coli
    FGF basic/bFGF Protein, Human (145a.a) is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts, with 145 amino acid.
  • HY-P72195
    FGF-23 Protein, Rat (His)

    Fgf23Fibroblast growth factor 23; FGF-23

    Rat E. coli
  • HY-P70597
    KGF/FGF-7 Protein, Human (163a.a)

    Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF

    Human E. coli
  • HY-P7066
    FGF-2 Protein, Mouse (145a.a)

    rMubFGF; HBGF-2; FGF-2; FGF-b; FGF-basic

    Mouse E. coli
    FGF-2 Protein, Mouse (145a.a) is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts.
  • HY-P7170
    KGF-2/FGF-10 Protein, Mouse

    rMuFGF-10; Keratinocyte growth factor-2; Fgf10

    Mouse E. coli
    KGF-2/FGF-10 Protein, Mouse is a paracrine signaling molecule and is involved in the branching of morphogenesis in multiple organs such as the lungs, skin, ear and salivary glands.
  • HY-P70533
    FGF-8b Protein, Human/Mouse

    Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B

    Human; Mouse E. coli
  • HY-P70440
    FGF basic/bFGF Protein, Human (157a.a)

    Fibroblast Growth Factor 2; FGF-2; Basic Fibroblast Growth Factor; bFGF; Heparin-Binding Growth Factor 2; HBGF-2; FGF2; FGFB

    Human E. coli
  • HY-P7179
    FGF-basic/bFGF protein, Bovine

    rBobFGF; FGF-2; FGF2; FGF 2; HBGF-2

    Bovine E. coli
    FGF-basic/bFGF protein, Bovine has a wide range of biological effects, including mitogenesis, cell survival, and formation of metastases.
  • HY-P7001
    FGF-1 Protein, Human

    rHuaFGF; HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic

    Human E. coli
    FGF-1 Protein, Human is a growth factor and signaling protein encoded by the FGF1 gene.
  • HY-P7012
    FGF-21 Protein, Human

    rHuFGF-21; Fibroblast Growth Factor-21(FGF-21)

    Human E. coli
    FGF-21 Protein, Human is an atypical member of the fibroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.
  • HY-P7342
    KGF-2/FGF-10 Protein, Human (His)

    rHuFGF-10, His; Fibroblast Growth Factor-10; Keratinocyte growth factor-2

    Human E. coli
    KGF-2/FGF-10 Protein, Human (His) is a polypeptide chain with His Tag. FGF-10 is a heparin-binding growth factor that belongs to the FGF family.
Cat. No. Product Name Effect Purity