1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-2 family (γc-family cytokines)

IL-2 family (γc-family cytokines)

Interleukin-2 (IL-2) is a pleiotropic cytokine which drives T-cell growth, augments NK cytolytic activity, induces the differentiation of regulatory T cells, and mediates activation-induced cell death. IL-2 acts by interaction with its receptors, which are composed of 3 subunits (IL-Rα, IL-2Rβ, and IL-2Rγ). IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 form a family of four α-helical bundle type I cytokines that share the common cytokine receptor γ chain, γc, as a key receptor component. Subsequently, these cytokines were classified into the same family, the IL-2 family (also called the common γ-chain family or γc family). The IL-2 family members each activate signal transducer and activator of transcription (STAT) proteins through phosphorylation of Janus kinase (JAK1 and JAK3). The γ chain is mutated in humans with X-linked severe combined immunodeficiency (XSCID), a disease in which T and natural killer (NK) cells are greatly diminished and B cells are non-functional.

Cat. No. Product Name / Synonyms Species Source
  • HY-P70646
    IL-2 Protein, Mouse (His)

    aldesleukin; interleukin 2; interleukin-2; IL-2; IL2; T-cell growth facter; T cell growth factor; TCGF

    Mouse E. coli
  • HY-P70655
    IL-15R alpha & IL-15 Fusion Protein, Human (HEK293, Fc)

    IL15RA& IL15; Interleukin-15; IL-15; IL15; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin-15 receptor subunit alpha

    Human HEK 293
  • HY-P7077
    IL-2 Protein, Mouse

    rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Mouse E. coli
    IL-2 Protein, Mouse is an immunomodulatory cytokine with widely varying functions including promotion of apoptosis, proliferation and survival of lymphocytes.
  • HY-P7037
    IL-2 Protein, Human

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human E. coli
    IL-2 Protein, Human is an adjunctive immunotherapeutic agent to treat tuberculosis (TB).
  • HY-P70644
    IL-4 Protein, Mouse

    Interleukin-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; IGG1 induction factor; Lymphocyte stimulatory factor 1; IL-4; BSF-1

    Mouse E. coli
    IL-4 Protein, Mouse is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression.
  • HY-P70750G
    GMP IL-4 Protein, Human (HEK 293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
  • HY-P70776G
    GMP IL-15 Protein, Human

    Interleukin-15; IL-15; IL15

    Human E. coli
  • HY-P70755G
    GMP IL-7 Protein, Human (HEK 293, His)

    Interleukin-7; IL-7; IL7

    Human HEK293
  • HY-P7080
    IL-4 Protein, Mouse (CHO)

    rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Mouse CHO
    IL-4 Protein, Mouse (CHO) is a species-specific cytokine which promotes the proliferation, differentiation and cell-surface protein modulation of B lymphocytes.
  • HY-P7038
    IL-21 Protein, Human

    rHuIL-21; Za11; IL21

    Human E. coli
    IL-21 Protein, Human is a class 1 cytokine, which is produced by activated CD4+ T cells. IL-21 Protein stimulation of T cells, B cells and NK cells leads to enhanced proliferation and mature effector function.
  • HY-P7037A
    IL-2 Protein, Human (CHO)

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human CHO
    IL-2 Protein, Human (CHO) is a CHO cell derived adjunctive immunotherapeutic agent to treat tuberculosis (TB).
  • HY-P70758
    IL-2 Protein, Human (HEK 293, His)

    Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

    Human HEK293
  • HY-P70445
    IL-4 Protein, Human

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human E. coli
    IL-4 Protein, Human is a potent lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells.
  • HY-P70653
    IL-4 Protein, Mouse (HEK293, His)

    Interleukin-4; IL-4; IL4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; Lymphocyte stimulatory factor 1

    Mouse HEK293
    IL-4 Protein, Mouse (HEK293, His) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 Protein, Mouse (HEK293, His) is a recombinant human interleukin-4 (rhIL-4) expressed in HEK 293 cells with a His tag.
  • HY-P7034
    IL-15 Protein, Human

    rHuIL-15; IL15

    Human E. coli
    IL-15 Protein, Human is a pleiotropic cytokine, including T, B and NK cell-stimulatory activities.
  • HY-P7045
    IL-7 Protein, Human

    rHuIL-7; LP-1; pre-B cell factor

    Human E. coli
    IL-7 Protein, Human, a hematopoietic cytokine, promotes T-cell recovery after allogeneic stem cell transplantation.
  • HY-P70750
    IL-4 Protein, Human (HEK293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
    IL-4 Protein, Human (HEK293) is a potent lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells. IL-4 Protein, Human (HEK293) is a recombinant human interleukin-4 (rhIL-4) expressed in HEK 293 cells.
  • HY-P7219
    IL-4 Protein, Porcine (CHO)

    rPoIL-4; BSF-1; IL4

    Porcine CHO
    IL-4 Protein, Porcine (CHO) is the prime anti-infalmmatory cytokine involves in cell proliferation, various gene expression and avert apoptosis in IL-4 expressing cells.
  • HY-P7078
    IL-21 Protein, Mouse (129a.a)

    rMuIL-21; Za11; IL21

    Mouse E. coli
    IL-21 Protein, Mouse (129a.a) is a regulatory cytokine thought to play a role in the transition between innate and adaptive immunity.
  • HY-P7038G
    GMP IL-21 Protein, Human

    Interleukin-21; IL-21; Za11; IL21

    Human E. coli
Cat. No. Product Name Effect Purity