1. Recombinant Proteins
  2. Immune Checkpoint Proteins
  3. Inhibitory checkpoint molecules
  4. PD-1 & PD-L1 (PD-L2)

Programmed death 1 (PD-1), also known as CD279, belongs to CD28 superfamily. PD-1 is an inhibitory receptor that is expressed on CD4+ and CD8+ T cells, NK cells, B cells, monocytes, and dendritic cells. PD-1 interacts with the ligands PD-L1 (B7-H1) and PD-L2 (B7-DC), which serves as a “rheostat” of immunological regulation, suppressing the activation and function of T cells to downregulate the immune response. PD-1 and its ligands play a fundamental role in the evasion of tumor cells from antitumor immunity. Moreover, PD-1 and PD-L1 is recognized as powerful targets to enhance tumor-directed cytotoxic T-cell function. In addition, PD-1/PD-L1 axis also regulates antiviral immune responses. (Targeting PD-1/PD-L1 )

Cat. No. Product Name / Synonyms Species Source
  • HY-P7396
    PD-1 Protein, Human (143a.a, HEK293, His)

    rHuPD-1, His; PD1; CD279; PDCD1

    Human HEK 293
    PD-1 Protein, Human (143a.a, HEK293, His) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70632
    PD-L1 Protein, Mouse (HEK 293, His)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274

    Mouse HEK293
  • HY-P7395
    PD-1 Protein, Human (CHO, Fc)

    rHuPD-1, Fc Chimera; PD1; CD279; PDCD1

    Human CHO
    PD-1 Protein, Human (CHO, Fc) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70633
    PD-L1 Protein, Mouse (220a.a, HEK 293, Fc)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274;

    Mouse HEK293
  • HY-P70640
    PD-1 Protein, Mouse (HEK 293, His)

    Programmed cell death protein 1; PD-1; CD279; Pdcd1; mPD-1

    Mouse HEK293
  • HY-P73363
    PD-L1 Protein, Mouse (239a.a, HEK293, Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
  • HY-P73716
    PD-L1 Protein, Mouse (HEK293, His-Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
  • HY-P70734
    PD-L2 Protein, Human (HEK 293, mFc)

    Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2

    Human HEK293
  • HY-P7397
    PD-L1 Protein, Human (CHO, Fc)

    rHuPD-L1, Fc Chimera; Programmed death ligand 1; CD274; B7-H1

    Human CHO
    PD-L1 Protein, Human (CHO, Fc) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P7398
    PD-L1 Protein, Human (HEK293, His)

    rHuPD-L1, His; Programmed death ligand 1; CD274; B7-H1

    Human HEK 293
    PD-L1 Protein, Human (HEK293, His) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P70639
    PD-1 Protein, Mouse (HEK 293, Fc)

    Programmed cell death protein 1; PD-1; CD279; Pdcd1; mPD-1

    Mouse HEK293
  • HY-P70663
    PD-L1 Protein, Human (HEK 293, Flag)

    Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1; Programmed Death Ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

    Human HEK293
  • HY-P7399
    PD-L2 Protein, Human (HEK293, Fc)

    rHuPD-L2, Fc Chimera; Programmed cell death 1 ligand 2; B7DC; CD273

    Human HEK 293
    PD-L2 Protein, Human (HEK293, Fc), a second ligand for PD-1, interacts with PD-1 negatively regulates T cell proliferation, cytokine production and cytotoxic activity.
  • HY-P70525
    PD-1 Protein, Human (HEK 293, mFc)

    Programmed cell death protein 1; hPD-1; PDCD1; CD279

    Human HEK293
  • HY-P70547
    PD-1 Protein, Cynomolgus (143a.a, HEK 293, Fc)

    Programmed cell death 1; PD-1; PD1

    Cynomolgus HEK293
  • HY-P70564
    PD-L1 Protein, Cynomolgus (HEK 293, His)

    B7-H; B7H1; B7-H1; PDCD1L1; CD274 molecule; CD274; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PD-L1B7 homolog 1; PDL1PDCD1 ligand 1; programmed cell death 1 ligand 1; Programmed death ligand 1

    Cynomolgus HEK293
  • HY-P70657
    PD-L1 Protein, Human (HEK 293, mFc)

    Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1; Programmed Death Ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

    Human HEK293
  • HY-P70672
    PD-L1 Protein, Human (221a.a, HEK 293, Fc)

    Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1; Programmed Death Ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

    Human HEK293
  • HY-P70676
    PD-1 Protein, Cynomolgus (147a.a, HEK 293, His)

    Programmed cell death 1; PD-1; PD1

    Human HEK293
  • HY-P70721
    PD-L1 Protein, Human (Biotinylated, HEK 293, Fc-Avi)

    Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

    Human HEK293
Cat. No. Product Name Effect Purity