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Results for "

pigr

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

7

Recombinant Proteins

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Cat. No. Compare Product Name Species Source
  • HY-P71065
    PIGR Protein, Human (HEK293, His)

    Polymeric Immunoglobulin Receptor; pigr; Poly-Ig Receptor; Hepatocellular Carcinoma-Associated Protein TB6; pigr

    		 Human HEK293
    PIGR proteins play a critical role in mediating the selective transcytosis of polymerized IgA and IgM across mucosal epithelial cells, which is critical for mucosal immunity. PIGR binds these immunoglobulins at the basolateral surface, forming a complex that is transported intracellularly and secreted apically. PIGR Protein, Human (HEK293, His) is the recombinant human-derived PIGR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PIGR Protein, Human (HEK293, His) is 620 a.a., with molecular weight of ~88.0 kDa.
  • HY-P74631
    PIGR Protein, Mouse (HEK293, His)

    Polymeric Immunoglobulin Receptor; Poly-Ig Receptor; pigr

    		 Mouse HEK293
    PIGR proteins mediate the selective transcytosis of polymerized IgA and IgM across mucosal epithelial cells. It binds to these immunoglobulins at the basolateral surface, forming complexes that are transported intracellularly and secreted at the apical surface. PIGR Protein, Mouse (HEK293, His) is the recombinant mouse-derived PIGR protein, expressed by HEK293 , with C-His labeled tag. The total length of PIGR Protein, Mouse (HEK293, His) is 627 a.a., with molecular weight of 90-100 kDa.
  • HY-P73377
    PIGR Protein, Human (G365S, HEK293, His)

    Polymeric Immunoglobulin Receptor; Poly-Ig Receptor; pigr

    		 Human HEK293
    PIGR Protein plays a crucial role in mediating the selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells, essential for mucosal immunity. Binding these immunoglobulins at the basolateral surface, PIGR forms a complex transported across the cell and secreted apically. Through N-linked glycans, PIGR anchors secretory IgA (sIgA) to mucosal surfaces, neutralizing pathogens. In its free form, PIGR also acts as a microbial scavenger, contributing to the defense against infections. PIGR Protein, Human (G365S, HEK293, His) is the recombinant human-derived PIGR protein, expressed by HEK293 , with C-His labeled tag and G365S mutation. The total length of PIGR Protein, Human (G365S, HEK293, His) is 638 a.a., with molecular weight of 80-90 kDa.
  • HY-P78011
    OSCAR Protein, Human (HEK293, Fc)

    mOSCAR; OSCAR; pigr3; pigr-3; Poly-Ig receptor 3; MGC33613

    		 Human HEK293
    OSCAR Protein, a key orchestrator in bone biology, crucially regulates osteoclastogenesis, influencing osteoclast differentiation, formation, and maturation. Focused on bones, OSCAR plays a pivotal role in maintaining skeletal homeostasis and structural integrity, contributing to the dynamic equilibrium of bone remodeling. OSCAR Protein, Human (HEK293, Fc) is the recombinant human-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of OSCAR Protein, Human (HEK293, Fc) is 211 a.a., with molecular weight of 60-70 kDa.
  • HY-P78012
    OSCAR Protein, Mouse (HEK293, Fc)

    mOSCAR; OSCAR; pigr3; pigr-3; Poly-Ig receptor 3; MGC33613

    		 Mouse HEK293
    OSCAR Protein is a crucial regulator of osteoclastogenesis, playing a significant role in osteoclast differentiation within the bone. OSCAR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of OSCAR Protein, Mouse (HEK293, Fc) is 210 a.a., with molecular weight of 60-70 kDa.
  • HY-P700674
    CD300a/LMIR1 Protein, Cynomolgus (HEK293, His)

    IGSF12; IRp60; CLM-8; IRC1; CD300a; CLM8; LMIR1; MAIR-I; Mcipr1; NKRL; pigr4

    		 Cynomolgus HEK293
    CD300a/LMIR1 Protein, an inhibitory receptor, potentially diminishes cytolytic activity in NK cells and suppresses mast cell degranulation. It serves as a negative regulator in MYD88-mediated TLR signaling, activating PTPN6 but not TRIF. Upon tyrosine phosphorylation, CD300a/LMIR1 engages with PTN6/SHP-1, PTPN11/SHP-2, and INPP5D, showcasing its multifaceted involvement in immune regulation and cellular responses. CD300a/LMIR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD300a/LMIR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD300a/LMIR1 Protein, Cynomolgus (HEK293, His) is 161 a.a., with molecular weight of 45-50 kDa.
  • HY-P78266
    CD300a/LMIR1 Protein, Mouse (HEK293, His)

    CMRF-35-H9; CMRF35-H9; CMRF35-H; IGSF12; IRp60; CLM-8; IRC1; IRC1/IRC2; IRC2; CD300a molecule; CD300a; CLM8; CMRF35HIRp60; LMIR1; MAIR-I; Mcipr1; NKRL; pigr4

    		 Mouse HEK293
    CD300a/LMIR1 protein inhibits cytolytic activity in NK cells and mast cell degranulation. It negatively regulates TLR signaling via MYD88 and PTPN6 activation, but not TRIF. CD300a/LMIR1 interacts with PTN6/SHP-1, PTPN11/SHP-2, and INPP5D upon tyrosine phosphorylation. CD300a/LMIR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD300a/LMIR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD300a/LMIR1 Protein, Mouse (HEK293, His) is 158 a.a., with molecular weight of 35-50 kDa.

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