1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. VEGFs & VEGFRs
  4. VEGFs

Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides that are crucial to the normal development and maintenance of the vascular and lymphatic systems. VEGFs belong to the VEGF/PDGF group of the cystine-knot superfamily of signaling molecules, which are all characterized by having a cystine-knot structure formed by eight cysteine residues. VEGFs have been found in all vertebrate species so far examined and are highly conserved between species. VEGF-A, also called VEGF, is the prototypical member of VEGF family that includes placental growth factor (PLGF), VEGF-B, VEGF-C, and VEGF-D (also known as c-Fos-induced growth factor, FIGF), and the viral VEGF-Es. Among them, VEGF-A exists in four different isoforms (comprising 121, 165, 189 and 206 amino acids in humans), which are generated by alternative splicing of a single pre-mRNA species. VEGF-A is a mitogen and survival factor for vascular endothelial cells while also promoting vascular endothelial cell and monocyte motility. VEGF-B also promotes angiogenesis. VEGF-C participates in lymphangiogenesis during embryogenesis and in the maintenance of differentiated lymphatic endothelium in adults. VEGF-D stimulates growth of vascular and lymphatic endothelial cells. Although first described in the placenta, PlGF is expressed in a wide variety of cells, tissues, and organs and participates inangiogenesis, wound healing, and the inflammatory response.

Cat. No. Product Name / Synonyms Species Source
  • HY-P70458
    VEGF165 Protein, Human (165a.a, HEK293)

    Vascular Endothelial Growth Factor Isoform 165; VEGF165

    Human HEK293
    VEGF165 Protein, Human (165a.a, HEK293) is a recombinant VEGF165 produced in HEK293 cells. VEGF165 is a heparin-binding growth factor with mitogenic activity for vascular endothelial cells.
  • HY-P7110A
    VEGF165 Protein, Human (HEK293)

    rHuVEGF165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen

    Human HEK293
    VEGF165 Protein, Human (HEK293) is a Vascular Endothelial Growth Factor A (VEGF-A) isoform. VEGF is a heparin-binding growth factor specific for vascular endothelial cells that is able to induce angiogenesis.
  • HY-P7313
    VEGF-C Protein, Human (116a.a, HEK293)

    rHuVEGF-C; Vascular endothelial growth factor C; Flt4-L; VRP

    Human HEK293
    VEGF-C Protein, Human (116a.a, HEK293) functions in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration.
  • HY-P7110
    VEGF165 Protein, Human (P.pastoris)

    rHuVEGF165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen

    Human P. pastoris
    VEGF165 Protein, Human (P.pastoris) is a Vascular Endothelial Growth Factor A (VEGF-A) isoform. VEGF is a heparin-binding growth factor specific for vascular endothelial cells that is able to induce angiogenesis.
  • HY-P7312
    VEGF164 Protein, Mouse

    rMuVEGF164; VEGF-A; VPF

    Mouse E. coli
    VEGF164 Protein, Mouse is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1.
  • HY-P70519
    VEGF121 Protein, Human (115a.a, HEK 293, His)

    Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGF

    Human HEK293
  • HY-P73529
    VEGF-C Protein, Human (125a.a, HEK293, His)

    Flt4-L; vascular endothelial growth factor C; VEGFC; VRP

    Human HEK293
  • HY-P7311
    VEGF165 Protein, Rat (CHO)

    rRtVEGF165; VEGF-A; VPF

    Rat CHO
    VEGF165 Protein, Rat (CHO) is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1.
  • HY-P7314
    VEGF-D Protein, Human (HEK293)

    rHuVEGF-D; Vascular endothelial growth factor D; FIGF

    Human CHO
    VEGF-D Protein, Human (HEK293) is a regulator of both angiogenesis and lymphangiogenesis.
  • HY-P74626
    PLGF Protein, Human (HEK293, mFc)

    Placenta growth factor; PlGF; PGF; PGFL

    Human HEK293
  • HY-P70521
    VEGF121 Protein, Human (115a.a)

    Vascular endothelial growth factor A; VEGFA; VEGF-A; Vascular permeability factor; VPF; VEGF; VEGF121

    Human E. coli
  • HY-P73471
    VEGF121 Protein, Human (HEK293)

    MVCD1; VAS; Vascular endothelial growth factor A; VEGF; VEGFA; VPF

    Human HEK293
  • HY-P7420
    VEGF121 Protein, Human (205a.a)

    rHuVEGF-121; VEGF-A; VPF

    Human E. coli
    VEGF121 Protein, Human (205a.a), a VEGF isoform splice variant, cannot bind to heparin. VEGF121 Protein is predictor for survival in activated B-cell-like diffuse large B-cell lymphoma and is related to an immune response gene signature conserved in cancers.
  • HY-P7421
    VEGF164 Protein, Mouse (186a.a, P.pastoris)

    rMuVEGF164; VEGF-A; VPF

    Mouse P. pastoris
    VEGF164 Protein, Mouse (186a.a, P.pastoris), a VEGF isoform splice variant, is more potent at inducing endothelial ICAM-1 expression by VEGFR-2, leukocyte migration by VEGFR-1, and inflammation and angiogenesis in the adult cornea.
  • HY-P70495
    VEGF-D Protein, Human (HEK 293, His)

    Vascular Endothelial Growth Factor D; VEGF-D; c-Fos-Induced Growth Factor; FIGF; VEGFD

    Human HEK293
  • HY-P70501
    VEGF-C Protein, Human (196a.a, HEK 293, His)

    Vascular Endothelial Growth Factor C; VEGF-C; Flt4 Ligand; Flt4-L; Vascular Endothelial Growth Factor-Related Protein; VRP; VEGFC

    Human HEK293
  • HY-P70638
    VEGF164 Protein, Rat (P.pastoris)

    Vascular endothelial growth factor A; Vascular permeability factor; VEGF; VEGF-A; VPF

    Rat P. pastoris
  • HY-P70749
    PLGF-2 Protein, Human (HEK 293, His)

    PlGF2; PlGF-2; PGF; PLGF; PlGF2; PlGF; PGFL

    Human HEK293
  • HY-P70761
    VEGF164 Protein, Mouse (1654a.a, P.pastoris)

    Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGFA164; VEGF164

    Mouse P. pastoris
  • HY-P70792
    PLGF Protein, Mouse (HEK 293, His)

    Placenta growth factor; PlGF; Plgf; D12S1900; PGFL; PLGF; PlGF-2; SHGC-10760

    Mouse HEK293
Cat. No. Product Name Effect Purity