1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. Puwainaphycin F

Puwainaphycin F 

Cat. No.: HY-131000
Handling Instructions

Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization.

For research use only. We do not sell to patients.

Puwainaphycin F Chemical Structure

Puwainaphycin F Chemical Structure

CAS No. : 1379577-47-5

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Description

Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].

In Vitro

Puwainaphycin F has an IC50 of 2.19 μM in HeLa cells[1].

Molecular Weight

1146.34

Formula

C₅₃H₈₇N₁₃O₁₅

CAS No.

1379577-47-5

SMILES

O=C(N1CCC[[email protected]]1(C(NC(C(CCCCCCCCCC)C)C(O)C(N[[email protected]@H](C(C)C)C(N/C(C(N[[email protected]]2CC(N)=O)=O)=C/C)=O)=O)=O)[H])[[email protected]](CC(N)=O)N(C)C([[email protected]]([H])([[email protected]@H](C)O)NC(C(C)NC([[email protected]](CC(N)=O)NC(/C(NC2=O)=C\C)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Puwainaphycin FADC CytotoxinInhibitorinhibitorinhibit

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