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(R)-FT671 

Cat. No.: HY-107985A Purity: 95.13%
Handling Instructions

(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM.

For research use only. We do not sell to patients.

(R)-FT671 Chemical Structure

(R)-FT671 Chemical Structure

CAS No. : 1959551-27-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 223 In-stock
Estimated Time of Arrival: December 31
5 mg USD 190 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1250 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-FT671:

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Description

(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM[1].

Molecular Weight

533.48

Formula

C₂₄H₂₃F₄N₇O₃

CAS No.

1959551-27-9

SMILES

O=C1C2=C(N(C3=CC=C(F)C=C3)N=C2)N=CN1CC4(O)CCN(C(C[[email protected]@H](N5N=C(F)C=C5)C(F)F)=O)CC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (281.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8745 mL 9.3724 mL 18.7448 mL
5 mM 0.3749 mL 1.8745 mL 3.7490 mL
10 mM 0.1874 mL 0.9372 mL 1.8745 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 7.5 mg/mL (14.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 7.5 mg/mL (14.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 7.5 mg/mL (14.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

(R)-FT671OthersUSP7Inhibitorinhibitorinhibit

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(R)-FT671
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HY-107985A
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