1. Apoptosis
  2. Apoptosis
  3. (±)-Norcantharidin

(±)-Norcantharidin (Synonyms: (±)-NCTD)

Cat. No.: HY-N0291
Handling Instructions

(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects.

For research use only. We do not sell to patients.

(±)-Norcantharidin Chemical Structure

(±)-Norcantharidin Chemical Structure

CAS No. : 29745-04-8

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Description

(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects[1].

In Vitro

(±)-Norcantharidin ((±)-NCTD) inhibits HMC cell proliferation, induces apoptosis, and affects the cell cycle[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

168.15

Formula

C₈H₈O₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1486.77 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9471 mL 29.7354 mL 59.4707 mL
5 mM 1.1894 mL 5.9471 mL 11.8941 mL
10 mM 0.5947 mL 2.9735 mL 5.9471 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (12.37 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (12.37 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (12.37 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
(±)-Norcantharidin
Cat. No.:
HY-N0291
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