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  4. CAMKIV/CAMK4 Protein, Human (HEK293, GST)

CAMKIV/CAMK4 Protein, Human (HEK293, GST)

Cat. No.: HY-P75458
Handling Instructions

The CAMKIV/CAMK4 protein, a serine/threonine kinase, participates in transcriptional regulation across cell types. Its expression is widespread, with notable levels in the brain (RPKM 7.0), lymph nodes (RPKM 3.7), and 21 other tissues. This suggests its potential involvement in diverse physiological processes across multiple organs. CAMKIV/CAMK4 Protein, Human (HEK293, GST) is the recombinant human-derived CAMKIV/CAMK4 protein, expressed by HEK293 , with N-GST labeled tag. The total length of CAMKIV/CAMK4 Protein, Human (HEK293, GST) is 473 a.a., with molecular weight of ~100 kDa.

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Description

The CAMKIV/CAMK4 protein, a serine/threonine kinase, participates in transcriptional regulation across cell types. Its expression is widespread, with notable levels in the brain (RPKM 7.0), lymph nodes (RPKM 3.7), and 21 other tissues. This suggests its potential involvement in diverse physiological processes across multiple organs. CAMKIV/CAMK4 Protein, Human (HEK293, GST) is the recombinant human-derived CAMKIV/CAMK4 protein, expressed by HEK293 , with N-GST labeled tag. The total length of CAMKIV/CAMK4 Protein, Human (HEK293, GST) is 473 a.a., with molecular weight of ~100 kDa.

Background

The CAMKIV/CAMK4 protein, belonging to the serine/threonine protein kinase family and the Ca(2+)/calmodulin-dependent protein kinase subfamily, is a versatile enzyme with a restricted tissue distribution. It has been implicated in transcriptional regulation in diverse cell types, including lymphocytes, neurons, and male germ cells. With broad expression observed in various tissues, the CAMKIV/CAMK4 protein is notably prevalent in the brain (RPKM 7.0), lymph nodes (RPKM 3.7), and 21 other tissues, underscoring its potential involvement in diverse physiological processes across multiple organs.

Species

Human

Source

HEK293

Tag

N-GST

Accession

NP_001735.1 (M1-Y473)

Gene ID

814  [NCBI]

Molecular Construction
N-term
GST
CAMK4 (M1-Y473)
Accession # NP_001735.1
C-term
Synonyms
Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CAMK4; CAMK; CAMK-GR
Molecular Weight

Approximately 100 kDa

Purity

Greater than 82% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CAMKIV/CAMK4 Protein, Human (HEK293, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CAMKIV/CAMK4 Protein, Human (HEK293, GST)
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HY-P75458
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