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  5. CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His)

CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His)

Cat. No.: HY-P76221
Handling Instructions

CD30/TNFRSF8 Protein, the TNFSF8/CD30L receptor, critically regulates cellular growth and lymphoblast transformation. It activates NF-kappa-B signaling, modulating gene expression and contributing to diverse cellular processes. Interactions with key signaling molecules (TRAF1, TRAF2, TRAF3, and TRAF5) underscore its significance in mediating essential intracellular pathways for cellular responses and regulatory functions. CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is the recombinant mouse-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is 258 a.a., with molecular weight of ~26.6 KDa.

For research use only. We do not sell to patients.

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Description

CD30/TNFRSF8 Protein, the TNFSF8/CD30L receptor, critically regulates cellular growth and lymphoblast transformation. It activates NF-kappa-B signaling, modulating gene expression and contributing to diverse cellular processes. Interactions with key signaling molecules (TRAF1, TRAF2, TRAF3, and TRAF5) underscore its significance in mediating essential intracellular pathways for cellular responses and regulatory functions. CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is the recombinant mouse-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His) is 258 a.a., with molecular weight of ~26.6 KDa.

Background

CD30/TNFRSF8 Protein, serving as the receptor for TNFSF8/CD30L, plays a critical role in the regulation of cellular growth and the transformation of activated lymphoblasts. Additionally, it is involved in the modulation of gene expression through the activation of NF-kappa-B signaling, contributing to diverse cellular processes. The interaction with key signaling molecules, including TRAF1, TRAF2, TRAF3, and TRAF5, further underscores its significance in mediating intracellular pathways essential for cellular responses and regulatory functions.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q60846 (M1-T258)

Gene ID

21941  [NCBI]

Molecular Construction
N-term
CD30 (M1-T258)
Accession # Q60846
His
C-term
Synonyms
CD30L receptor; Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen
Molecular Weight

Approximately 26.6 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD30/TNFRSF8 Protein, Mouse (258a.a, HEK293, His)
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HY-P76221
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