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cd47-protein-mouse-hek293-fc

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  • HY-P78711
    CD47 Protein, Mouse (HEK293, Fc)

    cd47; MER6; IAP; OA3

    		 Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD47 Protein, Mouse (HEK293, Fc) is 122 a.a., with molecular weight of 60-70 kDa.

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