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CDO Protein, Human (HEK293, His)

Cat. No.: HY-P70070
Handling Instructions

CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDO Protein, Human (HEK293, His) is 918 a.a., with molecular weight of 120-135 kDa.

For research use only. We do not sell to patients.

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Description

CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDO Protein, Human (HEK293, His) is 918 a.a., with molecular weight of 120-135 kDa.

Background

CDO (Cell Adhesion Molecule-Related/Downregulated by Oncogenes) is a component of a cell-surface receptor complex crucial for mediating cell-cell interactions among muscle precursor cells. It plays a significant role in promoting the differentiation of myogenic cells. CDO is part of a complex that includes BOC, CDON, NEO1, cadherins, and CTNNB1, underscoring its involvement in intricate signaling networks. Additionally, CDO interacts with NTN3, PTCH1, and GAS1, suggesting its association with various signaling pathways. Notably, CDO engages with important signaling molecules such as DHH, IHH, and SHH, emphasizing its participation in pathways critical for cellular development and tissue patterning. The multifaceted interactions of CDO highlight its role as a key regulator in coordinating cellular processes during development. (

Species

Human

Source

HEK293

Tag

C-6*His

Accession

Q4KMG0 (D26-P943)

Gene ID
Molecular Construction
N-term
CDO (D26-P943)
Accession # Q4KMG0
6*His
C-term
Synonyms
rHuCell adhesion molecule-related/down-regulated by oncogenes/CDO, His; Cell adhesion molecule-related/down-regulated by oncogenes; CDON; CDO
AA Sequence

DLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPP

Molecular Weight

120-135 kDa

Purity

Greater than 85% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CDO Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CDO Protein, Human (HEK293, His)
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HY-P70070
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