1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EMAP-II Protein, Human

EMAP-II Protein, Human

Cat. No.: HY-P7156
Handling Instructions

EMAP-II Protein, Human is a proinflammatory cytokine and chemoattractant of macrophages.

For research use only. We do not sell to patients.

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  • Biological Activity

  • Technical Parameters

  • Properties

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Description

EMAP-II Protein, Human is a proinflammatory cytokine and chemoattractant of macrophages.

Background

EMAP II is a proinflammatory cytokine and chemoattractant of macrophages[1]. EMAP-II protein possesses a wide range of activities toward endothelial cells, neutrophils, and monocyte/macrophages in vitro. EMAP-II up-regulates endothelial E and P-selectin expression and release of von Willebrand factor. It is also chemotactic for neutrophils and monocytes and induces release of myeloperoxidase activity from neutrophils[2].

Species

Human

Source

E. coli

Tag

Tag Free

Accession

Q12904 (S147-K312)

Gene ID
Molecular Construction
N-term
EMAP-II (S147-K312)
Accession # Q12904
C-term
Synonyms
rHuEMAP-II; Endothelial-Monocyte A Activating Polypeptide II; EMAP-2; AIMP1
AA Sequence

SKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK

Molecular Weight

Approximately 18.2 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
References

EMAP-II Protein, Human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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EMAP-II Protein, Human
Cat. No.:
HY-P7156
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