ENTE Protein, S. aureus (Baculovirus, His)

ENTE Proteinas are staphylococcal enterotoxins that activate the host immune system by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction forms a ternary complex that activates T lymphocytes and induces the systemic release of proinflammatory cytokines. ENTE Protein, S. aureus (Baculovirus, His) is the recombinant Staphylococcus aureus-derived ENTE protein, expressed by Sf9 insect cells , with N-6*His labeled tag. The total length of ENTE Protein, S. aureus (Baculovirus, His) is 230 a.a., with molecular weight of ~28.4 kDa.

ENTE, a staphylococcal enterotoxin, plays a pivotal role in activating the host immune system by binding as unprocessed molecules to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction results in the formation of a ternary complex, which, in turn, activates a significant number of T-lymphocytes, triggering a systemic release of pro-inflammatory cytokines. Beyond its immunomodulatory functions, ENTE is implicated in the development of staphylococcal food poisoning syndrome, a condition characterized by symptoms such as intoxication, fever, and gastrointestinal distress. These activities highlight the impact of ENTE on both immune response pathways and pathological outcomes.

Staphylococcus aureus

Sf9 insect cells

N-6*His

P12993 (S28-T257)

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SEEINEKDLRKKSELQRNALSNLRQIYYYNEKAITENKESDDQFLENTLLFKGFFTGHPWYNDLLVDLGSKDATNKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWIDGKQTTVPIDKVKTSKKEVTVQELDLQARHYLHGKFGLYNSDSFGGKVQRGLIVFHSSEGSTVSYDLFDAQGQYPDTLLRIYRDNKTINSENLHIDLYLYTT

Approximately 28.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.