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fc-gamma-riiia-cd16a-protein-human-f176v-hek-293-his

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  • HY-P75209
    Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His)

    Low affinity immunoglobulin gamma fc region receptor III-A; fcriiia; fcR-10; cd16a; fcGR3A; IGFR3

    		 Human HEK293
    Fc gamma RIIIA/CD16a protein is a receptor for the Fc fragment of IgG and activates antibody-dependent cellular cytotoxicity (ADCC) upon binding to antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-His labeled tag and F176V, , , , mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His) is 192 a.a., with molecular weight of ~44.2 kDa.
  • HY-P72885
    Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi)

    Low affinity immunoglobulin gamma fc region receptor III-A; fcriiia; fcR-10; cd16a; fcGR3A; IGFR3

    		 Human HEK293
    Fc gamma RIIIA/CD16a Protein, a receptor for the Fc fragment of IgG, activates antibody-dependent cellular cytotoxicity (ADCC) upon binding antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells for efficient virus-infected cell elimination. Fc gamma RIIIA/CD16a regulates NK cell survival, proliferation, and prevents progenitor apoptosis. It forms signaling complexes, driving intracellular cascades for NK cell activation. The protein plays a crucial role in antitumor activities, triggering TNFA-dependent ADCC. In Dengue virus infection, it contributes to pathogenesis via antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and F176V mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi) is 192 a.a., with molecular weight of ~46 kDa.

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