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il-1rl2-protein-human-hek-293-fc

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P70625

    Interleukin-1 receptor-like 2; il1rl2; il-36 receptor; il-36R; il-1Rrp2; il1R-rp2;

    Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-1RL2 Protein, Human (HEK293, Fc) is 318 a.a., with molecular weight of 80-110 kDa.

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