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il-4r-alpha-cd124-protein-human--hek-293-mfc

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P70325

    rHuInterleukin-4 receptor subunit alpha/il-4 RA, mfc; Interleukin-4 receptor subunit alpha; il-4 receptor subunit alpha; il-4r subunit alpha; il-4r-alpha; il-4rA; cd124; il-4-binding protein; il4-BP; il4r; il4rA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal mFc-tag.

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