KLRG2 Protein, Human (P.pastoris, His)

KLRG2 Protein is a member of the killer cell lectin-like receptor (KLR) family, is a group of transmembrane proteins preferentially expressed in NK cells. Genetic variations in the gene KLRG2 may affect the Gleason score at diagnosis and thus the aggressiveness of prostate cancer. KLRG2 Protein, Human (P.pastoris, His) is the recombinant human-derived KLRG2 protein, expressed by P. pastoris , with N-His labeled tag. The total length of KLRG2 Protein, Human (P.pastoris, His) is 409 a.a., with molecular weight of ~44.9 kDa.

KLRG2, a member of the killer cell lectin-like receptor (KLR) family, is a group of transmembrane proteins preferentially expressed in NK cells. Another member of the family, KLRG1, is a lymphocyte co-suppressor or immune checkpoint receptor expressed primarily in late-differentiation effector and effector memory CD8+ T and NK cells. Genetic variations in the gene KLRG2 may affect the Gleason score at diagnosis and thus the aggressiveness of prostate cancer^[1][2][3].

Human

P. pastoris

N-His

A4D1S0 (1M-409Q)

346689  [NCBI]

MEESWEAAPGGQAGAELPMEPVGSLVPTLEQPQVPAKVRQPEGPESSPSPAGAVEKAAGAGLEPSSKKKPPSPRPGSPRVPPLSLGYGVCPEPPSPGPALVKLPRNGEAPGAEPAPSAWAPMELQVDVRVKPVGAAGGSSTPSPRPSTRFLKVPVPESPAFSRHADPAHQLLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTCCRCKELGLEKEDAALLPRAGLDGDEKLPRAVTLTGLPMYVKSLYWALAFMAVLLAVSGVVIVVLASRAGARCQQCPPGWVLSEEHCYYFSAEAQAWEASQAFCSAYHATLPLLSHTQDFLGRYPVSRHSWVGAWRGPQGWHWIDEAPLPPQLLPEDGEDNLDINCGALEEGTLVAANCSTPRPWVCAKGTQ

Approximately 44.9 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.