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  4. PKC iota Protein, Human (sf9, GST)

PKC iota Protein, Human (sf9, GST)

Cat. No.: HY-P74630
Handling Instructions

PKC iota proteins are members of the calcium-dependent cell adhesion protein family and play critical roles in cellular interactions. PKC iota acts through a calcium-dependent mechanism and exhibits a preference for homogeneous interacting, connecting cells. PKC iota Protein, Human (sf9, GST) is the recombinant human-derived PKC iota protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PKC iota Protein, Human (sf9, GST) is 587 a.a., with molecular weight of ~100 kDa.

For research use only. We do not sell to patients.

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Description

PKC iota proteins are members of the calcium-dependent cell adhesion protein family and play critical roles in cellular interactions. PKC iota acts through a calcium-dependent mechanism and exhibits a preference for homogeneous interacting, connecting cells. PKC iota Protein, Human (sf9, GST) is the recombinant human-derived PKC iota protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PKC iota Protein, Human (sf9, GST) is 587 a.a., with molecular weight of ~100 kDa.

Background

Cadherin-17, belonging to the family of calcium-dependent cell adhesion proteins, functions as a pivotal component in cellular interactions. Operating through a calcium-dependent mechanism, cadherins like CDH17 exhibit a propensity for homophilic interactions, preferentially engaging with themselves in connecting cells. This unique property positions cadherins to potentially contribute to the intricate sorting processes of heterogeneous cell types. Specifically, LI-cadherin, a subtype within this family, may play a crucial role in the morphological organization of vital organs such as the liver and intestine. This highlights the diverse and specialized functions that cadherins, including CDH17, fulfill in maintaining tissue integrity and structural organization within specific physiological contexts.

Species

Human

Source

Sf9 insect cells

Tag

N-GST

Accession

P41743 (M10-V596)

Gene ID
Molecular Construction
N-term
GST
PKC iota (M10-V596)
Accession # P41743
C-term
Synonyms
Protein kinase C iota type; PRKC-lambda/iota; nPKC-iota; PRKCI; DXS1179E
Molecular Weight

Approximately 100 kDa

Purity

Greater than 88% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

PKC iota Protein, Human (sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
PKC iota Protein, Human (sf9, GST)
Cat. No.:
HY-P74630
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