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pvr-cd155-protein-human-hek293-his

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P70807

    Poliovirus Receptor; Nectin-Like protein 5; NECL-5; cd155; pvr; PVS

    Human HEK293
    PVR/CD155 Protein, Human (HEK293, His) is a recombinant Human PVR expressed in HEK 293 cells with a His tag at the N-terminus. PVR, Human plays a role in cancer cell invasion and migration.
  • HY-P78402

    cd155; HVED; NECL5; Necl-5; nectin-like 5; pvr; PVS; Tage4; PVSFLJ25946; FLJ25946

    Human HEK293
    PVR/CD155 Protein plays a pivotal role in initiating natural killer (NK) cell effector functions by binding CD96 and CD226 receptors. These interactions form a mature immunological synapse, triggering adhesion, lytic granule secretion, interferon-gamma (IFN-gamma), and cytotoxicity in activated NK cells. PVR/CD155 facilitates NK cell-target cell modular exchange and PVR transfer, crucial in tumor cells. However, in tumors, this transfer may induce fratricide NK cell activation, allowing immune evasion. Additionally, PVR/CD155 is implicated in tumor cell invasion and migration. In microbial infections, it acts as a poliovirus receptor, potentially mediating axonal transport through interaction with DYNLT1. PVR/CD155 Protein, Human (HEK293, His-Avi) is the recombinant human-derived PVR/CD155 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of PVR/CD155 Protein, Human (HEK293, His-Avi) is 323 a.a., with molecular weight of 55-70 kDa.

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