1. Recombinant Proteins
  2. Recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed)

Recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed)

Cat. No.: HY-P7480
Handling Instructions

Recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed) expresses in HEK293 cells with an Fc fragment at the C-terminus. Activin receptor-like kinase 1 (ALK1) is a type I receptor for transforming growth factor-β (TGF-β) family proteins. ALK1 has an important role during vascular development[1].

For research use only. We do not sell to patients.

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50 μg $140 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuActivin Receptor-like Kinase 1, C-Fc; ALK-1; ACVRL1; Activin Receptor-like Kinase 1
Species

Human

Source

HEK 293

Accession

P37023

Gene ID

94

Molecular Weight

50-65 kDa

AA Sequence

DPVKPSRGPL VTCTCESPHC KGPTCRGAWC TVVLVREEGR HPQEHRGCGN LHRELCRGRP TEFVNHYCCD SHLCNHNVSL VLEATQPPSE QPGTDGQ

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed) (rHuActivin Receptor-like Kinase 1, C-Fc) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed) (rHuActivin Receptor-like Kinase 1, C-Fc) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

ALK1 may mediate TGF-β1 signal in endothelial cells. The ALK1 signaling pathway can inhibit TGF-β1-dependent transcriptional activation mediated by the known TGF-β1 type I receptor, ALK5[1].

Documentation
References
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Recombinant Human Activin Receptor-like Kinase 1, C-Fc (HEK293-expressed)
Cat. No.:
HY-P7480
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