1. Recombinant Proteins
  2. Recombinant Human Activin receptor type 2A, His (HEK293-expressed)

Recombinant Human Activin receptor type 2A, His (HEK293-expressed)

Cat. No.: HY-P7455
Handling Instructions

Recombinant Human Activin receptor type 2A, His (HEK293-expressed) is a recombinant protein that in humans is encoded by the ACVR2A gene and produced in HEK293 cells, has a His tag. Activin A receptor is the receptor which binds Activin A. Activin A increases inflammatory cytokines in macrophages[1].

For research use only. We do not sell to patients.

Recombinant Proteins

Recombinant Proteins-MedChemExpress
Size Price Stock
10 μg $110 Ask For Quote & Lead Time
50 μg $305 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species

Human

Source

HEK 293

Accession

P27037

Gene ID

92

Molecular Weight

Approximately 32.0 kDa

AA Sequence

AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPHHHHH H

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 1 mM DTT, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human Activin receptor type 2A, His (HEK293-expressed) (rHuActivin receptor type 2A, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Human Activin receptor type 2A, His (HEK293-expressed) (rHuActivin receptor type 2A, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Activin A is a member of the transforming growth factor-β superfamily and regulates a wide variety of cellular events, including regulation of growth and metastasis of cancer cells, apoptosis, proliferation, and differentiation of human embryonic stem cells. Activin A is also a critical mediator of inflammation[1].

Documentation
References
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Product Name:
Recombinant Human Activin receptor type 2A, His (HEK293-expressed)
Cat. No.:
HY-P7455
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