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recombinant-human-alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-mgat2-his-hek293-expressed

" in MedChemExpress (MCE) Product Catalog:

95

Inhibitors & Agonists

1

Fluorescent Dye

2

Biochemical Assay Reagents

5

Peptides

26

Inhibitory Antibodies

5

Natural
Products

2

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150097

    Biochemical Assay Reagents Others
    Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has high efficacy of rHSA with little or no adverse reaction .
    <em>Recombinant Human</em> Serum Albumin(rHSA)
  • HY-101979A
    Numidargistat dihydrochloride
    5+ Cited Publications

    CB-1158 dihydrochloride; INCB01158 dihydrochloride

    Arginase Cancer
    Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
    Numidargistat dihydrochloride
  • HY-101979
    Numidargistat
    5+ Cited Publications

    CB-1158; INCB01158

    Arginase Cancer
    Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
    Numidargistat
  • HY-103189

    Adenosine Receptor Cardiovascular Disease Neurological Disease
    VUF-5574 is a selective antagonist of adenosine A 3 receptor with a Ki of 4.03 nM for the recombinant human receptor .
    VUF-5574
  • HY-P1068A

    Bacterial Infection
    Recombinant human lysozyme (plant expression) is a conserved anti-bacterial protein that causes bacterial lysis and death by hydrolyzing bacterial cell wall peptidoglycan (PG). Recombinant human lysozyme (plant expression) can be used to study bacterial infections .
    <em>Recombinant human</em> lysozyme (plant expression)
  • HY-15314
    Ranirestat
    1 Publications Verification

    AS-3201

    Aldose Reductase Neurological Disease Metabolic Disease
    Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas .
    Ranirestat
  • HY-12199

    Tiprolisant

    Histamine Receptor Neurological Disease Endocrinology
    Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
    Pitolisant
  • HY-12199B
    Pitolisant hydrochloride
    1 Publications Verification

    Ciproxidine; BF 2649

    Histamine Receptor Neurological Disease Endocrinology
    Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
    Pitolisant hydrochloride
  • HY-112998

    Factor VIII Others
    Efmoroctocog alfa is a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc) that can be used for the research of haemophilia A .
    Efmoroctocog alfa
  • HY-101601

    TAK-427

    Histamine Receptor Inflammation/Immunology Endocrinology
    Bamirastine inhibits ligand binding to recombinant human histamine H1 receptors (rhH1R) with an IC50 value of 17.3 nM.
    Bamirastine
  • HY-12199A

    Tiprolisant oxalate

    Histamine Receptor Neurological Disease Endocrinology
    Pitolisant oxalate is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
    Pitolisant oxalate
  • HY-19303

    CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ) .
    CRA-2059
  • HY-19303A

    Ser/Thr Protease Inflammation/Immunology
    CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ) .
    CRA-2059 hydrochloride
  • HY-19303B

    Ser/Thr Protease Inflammation/Immunology
    CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ) .
    CRA-2059 TFA
  • HY-103483
    MD2-IN-1
    3 Publications Verification

    Toll-like Receptor (TLR) Inflammation/Immunology
    MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189  μM for the recombinant human MD2 (rhMD2).
    MD2-IN-1
  • HY-108828

    rhGAA

    Others Others
    Alglucosidase alfa is a hydrolytic lysosomal glycogen-specific recombinant human α-glucosidase product. Alglucosidase alfa can be used for Pompe disease research .
    Alglucosidase alfa
  • HY-16040
    AM095 free acid
    5+ Cited Publications

    LPL Receptor Inflammation/Immunology
    AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
    AM095 free acid
  • HY-101383
    PF-01247324
    1 Publications Verification

    Sodium Channel Neurological Disease
    PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker with an IC50 of 196 nM for recombinant human Nav1.8 channel.
    PF-01247324
  • HY-10397A
    MX1013
    2 Publications Verification

    CV1013; Z-VD-FMK

    Caspase Cancer
    MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC50 of 30 nM .
    MX1013
  • HY-109530

    Others Metabolic Disease
    Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus .
    Insulin lispro
  • HY-N0518
    Toddalolactone
    1 Publications Verification

    PAI-1 Cardiovascular Disease
    Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM .
    Toddalolactone
  • HY-P99693

    GC1102

    HBV Infection
    Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection .
    Lenvervimab
  • HY-122154

    Adenosine Deaminase Inflammation/Immunology
    FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects .
    FR234938
  • HY-108830

    Aryplase; BM-102

    Others Metabolic Disease
    Galsulfase (Aryplase, BM-102) is recombinant human N-acetylgalactosamine-4-sulfatase. Galsulfase (Aryplase, BM-102) can be used for mucopolysaccharidosis (MPS) research .
    Galsulfase
  • HY-P99262

    BAX69; Anti-human MIF recombinant Antibody

    Macrophage migration inhibitory factor (MIF) Cancer
    Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer .
    Imalumab
  • HY-P99288

    Pamrevlumab; Anti-human CTGF recombinant Antibody

    Apoptosis Cancer
    FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .
    FG-3019
  • HY-P99785

    HLX20

    PD-1/PD-L1 Cancer
    Opucolimab is an anti-PD-L1 recombinant human monoclonal antibody. Opucolimab can be used to synthesis antibody agent conjugates. Opucolimab can be used for the research of advanced solid tumors .
    Opucolimab
  • HY-P99337

    Ansuvimab-zyk; mAb114

    Filovirus Infection
    Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody that exhibits antiviral activity against Zaire ebolavirus. Ansuvimab binds to the glycoprotein on Zaire ebolavirus to block its entry into host cells .
    Ansuvimab
  • HY-P99889

    BRII-198

    SARS-CoV Infection
    Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) .
    Romlusevimab
  • HY-13862
    AZD1080
    5 Publications Verification

    GSK-3 Neurological Disease
    AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3α and GSK3β with pKi (IC50) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively.
    AZD1080
  • HY-122168

    Prostaglandin Receptor Inflammation/Immunology
    AAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with Kis of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectively .
    AAT-008
  • HY-P3533

    Integrin Cardiovascular Disease
    EILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis .
    EILEVPST
  • HY-15556
    GSK269962A
    2 Publications Verification

    GSK 269962

    ROCK Cardiovascular Disease Inflammation/Immunology
    GSK269962A (GSK 269962) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively. GSK269962A has anti-inflammatory and vasodilatory activities .
    GSK269962A
  • HY-15556A

    GSK 269962 hydrochloride

    ROCK Cardiovascular Disease Inflammation/Immunology
    GSK269962A hydrochloride (GSK 269962 hydrochloride) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively. GSK269962A hydrochloride has anti-inflammatory and vasodilatory activities .
    GSK269962A hydrochloride
  • HY-P99952

    SCT400

    CD20 Cancer
    Ripertamab (SCT400) is a recombinant, human-mouse chimeric anti-CD20 IgG1κ mAb. Ripertamab can be used for the research of hematological malignancies, including non-Hodgkin’s lymphoma (NHL) .
    Ripertamab
  • HY-P99792

    NM57; rhRIG

    RABV Infection
    Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .
    Ormutivimab
  • HY-14950

    JTT-705; RO4607381

    CETP Cardiovascular Disease Cancer
    Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
    Dalcetrapib
  • HY-133148

    Phospholipase Inflammation/Immunology
    Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2 .
    Lp-PLA2-IN-2
  • HY-133149

    Phospholipase Cardiovascular Disease
    Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 (rhLpPLA2) .
    Lp-PLA2-IN-3
  • HY-19958

    XEN907 is a potent and spirooxindole blocker of NaV1.7, with an IC50 of 3 nM. XEN907 also inhibits CYP3A4 in a recombinant human enzyme assay. XEN907 can be used for the research of pain .
    XEN907
  • HY-100405

    FTIDC is an orally active, noncompetitive, selective allosteric metabotropic glutamate receptor (mGluR) 1 antagonist with an IC50 of 5.8 nM for human mGluR1a. FTIDC has no species differences in its antagonistic activity on recombinant human, mouse, and rat mGluR1 .
    FTIDC
  • HY-103226
    SC-57461A
    1 Publications Verification

    Aminopeptidase Inflammation/Immunology
    SC-57461A is a potent, orally active, nonpeptide, and selective inhibitor of Leukotriene A4 (LTA4) hydrolase with IC50s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .
    SC-57461A
  • HY-P99908

    NT-17

    Interleukin Related Cancer
    Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .
    Efineptakin alfa
  • HY-19843

    MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes .
    MK-0941
  • HY-108905

    human IGF-I; FK 780

    IGF-1R Metabolic Disease
    Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .
    Mecasermin
  • HY-113482

    1β-OH-DCA

    Endogenous Metabolite Cytochrome P450 Metabolic Disease
    1β-Hydroxydeoxycholic acid (1β-OH-DCA), a secondary bile acid, is a CYP3A biomarker. Deoxycholic acid is specifically metabolized into 1β-Hydroxydeoxycholic acid by CYP3A4 and CYP3A7 using recombinant human CYP450 enzymes .
    1β-Hydroxydeoxycholic acid
  • HY-147389

    Phosphodiesterase (PDE) Cancer
    Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity .
    Enpp-1-IN-14
  • HY-108858

    rhDNase

    Others Others
    Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. Dornase alfa plays an important role in cystic fibrosis .
    Dornase alfa
  • HY-P99756

    MEDI8897

    RSV Infection
    Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with modified Fc region, which can prolong its half-life. Nirsevimab has an affinity for RSV-B with an Kd value of 1.5 nM. Nirsevimab can be used for RSV research .
    Nirsevimab
  • HY-N9892

    Sirtuin Others
    Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla .
    Guttiferone G

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