1. Recombinant Proteins
  2. Recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed)

Recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed)

Cat. No.: HY-P7521
Handling Instructions

Recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed) is a 35-45 kDa Anthrax toxin receptor 1 protein expressed by HEK293 cells. Human Anthrax toxin receptor 1 is a type I membrane protein with an extracellular von Willebrand factor A domain that binds directly to protective antigen (PA). Human Anthrax toxin receptor 1 is also identified as the high-affinity cellular receptor for Seneca Valley Virus (SVV)[1].

For research use only. We do not sell to patients.

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuAnthrax toxin receptor 1, His; ANTXR1; ATR; Anthrax toxin receptor 1
Species

Human

Source

HEK 293

Accession

Q9H6X2-4

Gene ID

84168

Molecular Weight

35-45 kDa

AA Sequence

EDGGPACYGG FDLYFILDKS GSVLHHWNEI YYFVEQLAHK FISPQLRMSF IVFSTRGTTL MKLTEDREQI RQGLEELQKV LPGGDTYMHE GFERASEQIY YENRQGYRTA SVIIALTDGE LHEDLFFYSE REANRSRDLG AIVYCVGVKD FNETQLARIA DSKDHVFPVN DGFQALQGII HSILKKSCIE ILAAEPSTIC AGESFQVVVR GNGFRHARNV DRVLCSFKIN DSVTLNEKPF SVEDTYLLCP APILKEVGMK AALQVSMNDG LSFISSSVII TTTHCSLHKH HHHHH

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed) (rHuAnthrax toxin receptor 1, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed) (rHuAnthrax toxin receptor 1, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Human Anthrax toxin receptor 1 is a type I membrane protein with an extracellular von Willebrand factor A domain that binds directly to protective antigen (PA). Human Anthrax toxin receptor 1 is also identified as the high-affinity cellular receptor for Seneca Valley Virus (SVV). Human ANTXR1 shares 99% aa identity with mouse and rat and 92% identity with dog and chick ANTXR1 within the extracellular domain[1].

Documentation
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Recombinant Human Anthrax toxin receptor 1, His (HEK293-expressed)
Cat. No.:
HY-P7521
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