1. Recombinant Proteins
  2. Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)

Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)

Cat. No.: HY-P7003
Handling Instructions

Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $90 In-stock
Estimated Time of Arrival: December 31
50 μg $290 In-stock
Estimated Time of Arrival: December 31
100 μg $490 Get quote
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Species

Human

Source

CHO

Accession

Q9Y275

Gene ID

10673

Molecular Weight

Approximately 17 kDa

AA Sequence

AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL

Biological Activity
The ED50 is <20 ng/mL as measured by human RPMI 8226 cells, corresponding to a specific activity of >5.0 × 104 units/mg.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

B-cell activating factor (BAFF), a member of the tumor necrosis factor (TNF) superfamily, is secreted by various myeloid cells such as macrophages, dendritic cells, and neutrophils. BAFF is a potent survival factor for B cells and plays an essential role in peripheral B-cell homeostasis[1].

Documentation
References
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Product Name:
Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)
Cat. No.:
HY-P7003
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