1. Recombinant Proteins
  2. Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)

Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)

Cat. No.: HY-P7215
Handling Instructions

Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed), also known at Tac antigen and a CD25, is a 42 kDa transmembrane protein. The interleukin 2 receptor alpha, beta and gamma chain constitute the high-affinity IL2 receptor.

For research use only. We do not sell to patients.

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50 μg $390 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuIL-2Rα, His; TAC-antigen; CD25
Species

Human

Source

HEK 293

Accession

P01589

Gene ID

3559

Molecular Weight

Approximately 42 kDa

AA Sequence

HHHHHHHHEL CDDDPPEIPH ATFKAMAYKE GTMLNCECKR GFRRIKSGSL YMLCTGNSSH SSWDNQCQCT SSATRNTTKQ VTPQPEEQKE RKTTEMQSPM QPVDQASLPG HCREPPPWEN EATERIYHFV VGQMVYYQCV QGYRALHRGP AESVCKMTHG KTRWTQPQLI CTGEMETSQF PGEEKPQASP EGRPESETSC

Biological Activity
The ED50 is <1.5 μg/mL as measured by murine CTLL-2 cells.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed) (rHuIL-2Rα, His) to 100 μg/mL using ddH2O or PBS.

Storage & Stability

Lyophilized recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed) (rHuIL-2Rα, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

The cytokine interleukin 2 (IL2) is produced by activated helper T lymphocytes and stimulates proliferation and effector functions of a variety of cells of the immune system. High-affinity IL2 receptors consist of three distinct components, the α chain (IL2Rα, 50-55 kD), the β chain (IL2Rβ, 70-75 kD) and the γ chain[1].

Documentation
References
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Product Name:
Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)
Cat. No.:
HY-P7215
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