1. Recombinant Proteins
  2. Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed)

Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed)

Cat. No.: HY-P7254
Handling Instructions

Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed) is a member of CC subfamily, exerting various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5.

For research use only. We do not sell to patients.

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Size Price Stock
10 μg $160 Ask For Quote & Lead Time
50 μg $420 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

rHuMIP-1α/CCL3; C-C motif chemokine 3; MIP1A; SCYA3






Gene ID


Molecular Weight

8-10 kDa

AA Sequence


Biological Activity
The ED50 is <100 ng/mL as measured by CHO/Gα15 cells.

Lyophilized powder.


Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.


Reconstitute the lyophilized recombinant Human MIP-1 alpha/CCL3 (CHO-expressed) (rHuMIP-1α/CCL3) to 100 μg/mL using ddH2O or PBS.

Storage & Stability

Lyophilized recombinant Human MIP-1 alpha/CCL3 (CHO-expressed) (rHuMIP-1α/CCL3) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.


CCL3 also known as macrophage inflammatory protein 1-a, is a member of the CC subfamily. It’s known that CCL3 is produced by monocytes/macrophages, lymphocytes, neutrophils as well as immune cells such as basophils, mast cells, fibroblasts, and dendritic cells. Meanwhile, CCL3 exerts various biological effects by binding to its three cell surface receptors, including CCR1, CCR3, and CCR5. MIP-1a induces a variety of pro-inflammatory activities such as leukocyte chemotaxis, and promotes the entry of T cells into the inflammatory tissue region from blood circulation. Chemotactic CD4+ cells, CD8+ cells, natural killer cells, and dendritic cells bind to the corresponding receptors and coordinate the occurrence of immune reactions in the immune response site by migrating through vascular endothelial cells. In addition, MIP-1a is considered as a key inflammatory mediator in granuloma, asthma, T1D as well as other autoimmune diseases[1].

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Recombinant Human MIP-1 alpha/CCL3 (CHO-expressed)
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