1. Recombinant Proteins
  2. Recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed)

Recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed)

Cat. No.: HY-P7646
Handling Instructions

Recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed), a TNF receptor that specifically interacts with BAFF, appears to be the principal receptor required for BAFF-mediated mature B cell survival and for generating an effective T cell-dependent immune response[1].

For research use only. We do not sell to patients.

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10 μg $75 Ask For Quote & Lead Time
50 μg $225 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rMuBAFFR/TNFRSF13C, C-Fc; BAFF R; BAFFR; BR3; CD268; TNFRSF13C
Species

Mouse

Source

HEK 293

Accession

Q9D8D0

Gene ID

72049

Molecular Weight

40-55 kDa

AA Sequence

SQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVA-Fctag

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Biological Activity
Immobilized Human BAFF-His at 10μg/mL (100 μL/well) can bind recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed). The ED50 of recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed) is 0.04ug/mL.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed) (rMuBAFFR/TNFRSF13C, C-Fc) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed) (rMuBAFFR/TNFRSF13C, C-Fc) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

BAFF-R, the major B cell–activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders. In mice, BAFF-R is required for B-cell maturation and survival, and in mice and humans, the overproduction of BAFF is associated with autoimmune disease. BAFF-R is up-regulated on T cells after stimulation through the TCR in vitro[2].

Documentation
References
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Product Name:
Recombinant Mouse BAFFR/TNFRSF13C, C-Fc (HEK293-expressed)
Cat. No.:
HY-P7646
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