1. Recombinant Proteins
  2. Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20

Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20

Cat. No.: HY-P7263
Handling Instructions

Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

For research use only. We do not sell to patients.

Recombinant Proteins

Recombinant Proteins-MedChemExpress
Size Price Stock
10 μg $160 Ask For Quote & Lead Time
50 μg $430 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rMuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20
Species

Mouse

Source

E. coli

Accession

O89093

Gene ID

20297

Molecular Weight

Approximately 8.0 kDa

AA Sequence

ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability

Lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2].

Documentation
References
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Product Name:
Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20
Cat. No.:
HY-P7263
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