1. Recombinant Proteins
  2. Recombinant Rat Interleukin-1 alpha (CHO-expressed)

Recombinant Rat Interleukin-1 alpha (CHO-expressed)

Cat. No.: HY-P7096
Handling Instructions

Recombinant Rat Interleukin-1 alpha (CHO-expressed) is a nonsecreted pro-inflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells and endothelial cells.

For research use only. We do not sell to patients.

Recombinant Proteins

Recombinant Proteins-MedChemExpress
Size Price Stock
10 μg $190 Ask For Quote & Lead Time
50 μg $490 Ask For Quote & Lead Time
100 μg $780 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

rRtIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha






Gene ID


Molecular Weight

17-22 kDa

AA Sequence


Biological Activity
The ED50 is <5 pg/mL as measured by D10S cells.

Lyophilized powder.


Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.


Reconstitute the lyophilized recombinant Rat Interleukin-1 alpha (CHO-expressed) (rRtIL-1α) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Rat Interleukin-1 alpha (CHO-expressed) (rRtIL-1α) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.


IL-1alpha and IL-1beta have potent effects on the central nervous system resulting in fever, activation of the hypothalamic-pituitary-adrenal axis and behavioural depression. IL-1alpha and IL-1beta show some species specificity in the potency of their biological activities, the objective of the present work was to directly compare the effects of recombinant rat IL-1alpha and IL-1beta in the rat system as a first step to dissect out the mechanisms that are involved in these effects. In vitro, recombinant rat IL-1alpha and IL-1beta bind with the same affinity as human IL-1 to the rat insulinoma Rin m5F cell line that mainly expresses type I IL-1 receptors. This binding activated IL-1 receptors, as shown by induction of the synthesis of TNF-alpha mRNA. In vivo, recombinant rat IL-1alpha and IL-1beta enhance body temperature, increase plasma levels of corticosterone and ACTH, and depress social behavior[1].

  • Molarity Calculator

  • Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Recombinant Rat Interleukin-1 alpha (CHO-expressed)
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