1. Recombinant Proteins
  2. Recombinant Rat Interleukin-1 beta

Recombinant Rat Interleukin-1 beta

Cat. No.: HY-P7097
Handling Instructions

Recombinant Rat Interleukin-1 beta is an immunomodulary cytokine that mediates a wide range of immune responses.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $190 In-stock
Estimated Time of Arrival: December 31
50 μg $490 In-stock
Estimated Time of Arrival: December 31
100 μg $780 In-stock
Estimated Time of Arrival: December 31
250 μg   Get quote  

* Please select Quantity before adding items.

Publications Citing Use of MCE Recombinant Rat Interleukin-1 beta

  • Technical Parameters

  • Properties

  • Description

Synonyms
rRtIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B
Species

Rat

Source

E. coli

Accession

Q5BKB0

Gene ID

24494

Molecular Weight

Approximately 17.3 kDa

AA Sequence

VPIRQLHCRL RDEQQKCLVL SDPCELKALH LNGQNISQQV VFSMSFVQGE TSNDKIPVAL GLKGLNLYLS CVMKDGTPTL QLESVDPKQY PKKKMEKRFV FNKIEVKTKV EFESAQFPNW YISTSQAEHR PVFLGNSNGR DIVDFTMEPV SS

Biological Activity
The ED50 is <10 pg/mL as measured by mouse D10S cells, corresponding to a specific activity of >1.0 × 108 units/mg.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Rat Interleukin-1 beta (rRtIL-1β) to 100 µg/mL using ddH2O.

Storage & Stability

Lyophilized recombinant Rat Interleukin-1 beta (rRtIL-1β) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Interleukin-1 beta (IL-1β) is a proinflammatory cytokine, produced in response to inflammatory agents by a variety of cells, including, monocytes, macrophages, and dendritic cells (DCs). Recombinant rat IL-1β and IL-6 synergistically enhance C3 mRNA levels and complement component C3 secretion by H-35 rat hepatoma cells. In rat hepatoma H-35 cells, recombinant rat IL-1β, IL-6, and IFN-γ increase the quantity of C3 mRNA and secreted C3 protein, an observation consistent with reports that C3 is an acute phase protein in the rat[1].

Documentation
References
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Recombinant Rat Interleukin-1 beta
Cat. No.:
HY-P7097
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