1. Recombinant Proteins
  2. Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed)

Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed)

Cat. No.: HY-P7261
Handling Instructions

Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed) is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.

For research use only. We do not sell to patients.

Recombinant Proteins

Recombinant Proteins-MedChemExpress
Size Price Stock
10 μg $190 Ask For Quote & Lead Time
50 μg $420 Ask For Quote & Lead Time

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rRtMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20
Species

Rat

Source

HEK 293

Accession

P97884

Gene ID

29538

Molecular Weight

Approximately 8.2 kDa

AA Sequence

ASNFDCCLTY TKNVYHHARN FVGFTTQMAD EACDINAIIF HLKSKRSVCA DPKQIWVKRI LHLLSLRTKK M

Biological Activity
The ED50 is <0.6 μg/mL as measured by CHO-K1/Gα15/rCCR6 cells (human Gα15 and rat CCR6 stably expressed in CHO-K1 cells).
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed) (rRtMIP-3α/CCL20) to 100 μg/mL using ddH2O or PBS.

Storage & Stability

Lyophilized recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed) (rRtMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2].

Documentation
References
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Product Name:
Recombinant Rat Macrophage Inflammatory Protein-3 alpha/CCL20 (HEK293-expressed)
Cat. No.:
HY-P7261
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