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serpin-b5-protein-human

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  • HY-P7054
    PEDF Protein, Human

    rHuPEDF; serpinF1; EPC-1

    		 Human E. coli
    PEDF Protein, Human is a secreted glycoprotein and a non-inhibitory member of the serine protease inhibitor (serpin) family.
  • HY-P77198
    Serpin B4 Protein, Human (sf9, His)

    serpin B4; Leupin; Peptidase inhibitor 11; PI-11; SCCA-2

    		 Human Sf9 insect cells
    Serpin B4 is a protease inhibitor that may modulate the host immune response against tumor cells, suggesting a crucial role in fine-tuning immune balance. Its ability to inhibit proteases emphasizes its importance in influencing key regulatory pathways, enhancing the immune system's effectiveness against cancer cells. Serpin B4 Protein, Human (sf9, His) is the recombinant human-derived Serpin B4 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B4 Protein, Human (sf9, His) is 390 a.a., with molecular weight of ~45 kDa.
  • HY-P73412
    Serpin A3 Protein, Human (HEK293, His)

    Alpha-1-Antichymotrypsin; ACT; serpin A3; serpinA3; AACT

    		 Human HEK293
    Serpin A3 protein is a serine protease inhibitor on chromosome 14 that affects protease targeting through tissue-specific polymorphisms. Sequence variants are associated with Alzheimer's disease, while deficiencies are associated with liver disease. Serpin A3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A3 Protein, Human (HEK293, His) is 398 a.a., with molecular weight of ~50-70 kDa.
  • HY-P73658
    Serpin A6 Protein, Human (HEK293, His)

    Corticosteroid-binding globulin; CBG; Transcortin; serpinA6

    		 Human HEK293
    Serpin A6 Protein functions as a vital transport protein, facilitating the transport of glucocorticoids and progestins in the bloodstream across various vertebrate species. Serpin A6 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A6 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A6 Protein, Human (HEK293, His) is 383 a.a., with molecular weight of 55-60 kDa.
  • HY-P7054A
    PEDF Protein, Human (His)

    rHuPEDF; serpinF1; EPC-1

    		 Human E. coli
    PEDF Protein, Human is a secreted glycoprotein and a non-inhibitory member of the serine protease inhibitor (serpin) family.
  • HY-P71079
    Serpin A7 Protein, Human (HEK293, His)

    Thyroxine-Binding Globulin; serpin A7; T4-Binding Globulin; serpinA7; TBG

    		 Human HEK293
    Serpin A7, or thyroxine-binding globulin (TBG), acts as a glycoprotein carrier for thyroid hormones, specifically binding and transporting thyroxine (T4) and triiodothyronine (T3). TBG regulates the availability and distribution of thyroid hormones critical for physiological processes like metabolism and growth. Mutations in the SERPINA7 gene can affect TBG function, influencing thyroid hormone levels. Serpin A7 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A7 Protein, Human (HEK293, His) is 395 a.a., with molecular weight of 55-65 kDa.
  • HY-P71306
    Serpin B9 Protein, Human (HEK293, His)

    Cytoplasmic antiproteinase 3; Peptidase inhibitor 9; CAP3; PI-9; serpin B9

    		 Human HEK293
    The Serpin B9 Protein, a member of the serpin family, crucially regulates immune responses by specifically inhibiting granzyme B, a protease involved in immune cell-mediated apoptosis. Acting as a potent inhibitor, Serpin B9 modulates granzyme B's cytotoxic activity, fine-tuning immune responses and preventing unwarranted cell death, emphasizing its significance in maintaining immune balance. Serpin B9 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B9 Protein, Human (HEK293, His) is 376 a.a., with molecular weight of 35-40 kDa.
  • HY-P77199
    Serpin D1 Protein, Human (HEK293, His)

    Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2

    		 Human HEK293
    Serpin D1 protein is a thrombin inhibitor activated by glycosaminoglycans such as heparin or dermatan sulfate. It replaces antithrombin III and becomes the main thrombin inhibitor in the presence of dermatan sulfate. In addition to thrombin inhibition, serpin D1 also has glycosaminoglycan-independent chymotrypsin inhibitory activity. Serpin D1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin D1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin D1 Protein, Human (HEK293, His) is 480 a.a., with molecular weight of ~75-80 kDa.
  • HY-P71304
    Serpin B12 Protein, Human (HEK293, His)

    serpinB12; serpin B12; Serine Protease Inhibitor-clade B12

    		 Human HEK293
    Serpin B12 Protein inhibits trypsin and plasmin, excluding thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. It may have a role in cell differentiation, interacting with SLFN12 in a pathway regulating differentiation, and potentially interacting with USP14. Serpin B12 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B12 Protein, Human (HEK293, His) is 425 a.a., with molecular weight of ~55.0 kDa.
  • HY-P73526
    Serpin G1 Protein, Human (500a.a, HEK293, His)

    C1IN; C1INH; serpinG1; serpin G1; Plasma protease C1 inhibitor

    		 Human HEK293
    Serpin G1, also known as C1-inhibitor, controls C1 complex activation by forming a proteolytically inactive complex with C1r or C1s proteases. Its interactions regulate physiological pathways like complement activation, blood coagulation, fibrinolysis, and kinin generation. As a potent inhibitor of FXIIa, chymotrypsin, and kallikrein, Serpin G1 binds to E. coli stcE, protecting against complement-mediated lysis, and engages with MASP1, showcasing its intricate involvement in various cellular processes. Serpin G1 Protein, Human (500a.a, HEK293, His) is the recombinant human-derived Serpin G1 protein, expressed by HEK293, with C-10*His labeled tag. The total length of Serpin G1 Protein, Human (500a.a, HEK293, His) is 478 a.a., with molecular weight of ~110 kDa.
  • HY-P73659
    Serpin A6 Protein, Human (Biotinylated, HEK293, His-Avi)

    Corticosteroid-binding globulin; CBG; Transcortin; serpinA6

    		 Human HEK293
    Serpin A6 Protein functions as a vital transport protein, facilitating the transport of glucocorticoids and progestins in the bloodstream across various vertebrate species. Serpin A6 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Serpin A6 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Serpin A6 Protein, Human (Biotinylated, HEK293, His-Avi) is 383 a.a., with molecular weight of ~45.9 kDa.
  • HY-P71143
    Serpin A4 Protein, Human (HEK293, His)

    Kallistatin; Kallikrein Inhibitor; Peptidase Inhibitor 4; PI-4; serpin A4; serpinA4; KST; PI4

    		 Human HEK293
    Serpin A4 Protein inhibits tissue kallikrein's amidolytic and kininogenase activities by forming a heat- and SDS-stable equimolar complex with the enzyme. Tissue kallikrein concurrently cleaves the reactive site of Serpin A4, producing a small C-terminal fragment. The protein, existing as a monomer and occasionally forming homodimers, demonstrates its regulatory role in modulating tissue kallikrein-mediated enzymatic activities. Serpin A4 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A4 Protein, Human (HEK293, His) is 407 a.a., with molecular weight of 60-80 kDa.
  • HY-P76720
    Alpha-2-Antiplasmin/Serpin F2 Protein, Human (HEK293, His)

    Alpha-2-AP; Alpha-2-plasmin inhibitor; Alpha-2-PI; AAP; PLI

    		 Human HEK293
    Alpha-2-Antiplasmin/Serpin F2 Protein, a serine protease inhibitor, primarily targets plasmin and trypsin, also inactivating matriptase-3/TMPRSS7 and chymotrypsin. It can form a heterodimer with TMPRSS7, enhancing its protease inhibitory activity. Alpha-2-Antiplasmin/Serpin F2 Protein, Human (HEK293, His) is the recombinant human-derived Alpha-2-Antiplasmin/Serpin F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Alpha-2-Antiplasmin/Serpin F2 Protein, Human (HEK293, His) is 491 a.a., with molecular weight of ~70 kDa.
  • HY-P70970
    Serpin B6 Protein, Human (Trx-His)

    serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI

    		 Human E. coli
    Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (Trx-His) is the recombinant human-derived Serpin B6 protein, expressed by E. coli , with N-Trx, N-6*His labeled tag. The total length of Serpin B6 Protein, Human (Trx-His) is 376 a.a., with molecular weight of 58-60 kDa.
  • HY-P72831
    Antithrombin III/Serpin C1 Protein, Human (432a.a, HEK293, His)

    Antithrombin-III; ATIII; serpin C1; serpinC1; AT3

    		 Human HEK293
    Antithrombin III/Serpin C1 protein, the main plasma serine protease inhibitor, regulates the blood coagulation cascade. It inhibits thrombin, matriptase-3/TMPRSS7, and factors IXa, Xa, and XIa, with enhanced potency in the presence of heparin. Furthermore, it forms a protease-inhibiting heterodimer with TMPRSS7. Antithrombin III/Serpin C1 Protein, Human (432a.a, HEK293, His) is the recombinant human-derived Antithrombin III/Serpin C1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Antithrombin III/Serpin C1 Protein, Human (432a.a, HEK293, His) is 432 a.a., with molecular weight of 55-60 kDa.
  • HY-P76640
    Serpin B6 Protein, Human (sf9, His)

    serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI

    		 Human Sf9 insect cells
    Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (sf9, His) is the recombinant human-derived Serpin B6 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B6 Protein, Human (sf9, His) is 375 a.a., with molecular weight of ~43 kDa.
  • HY-P72831A
    Antithrombin III/Serpin C1 Protein, Human (HEK293, C-His)

    Antithrombin-III; ATIII; serpin C1; serpinC1; AT3

    		 Human HEK293
    Antithrombin III/Serpin C1 protein, the main plasma serine protease inhibitor, regulates the blood coagulation cascade. It inhibits thrombin, matriptase-3/TMPRSS7, and factors IXa, Xa, and XIa, with enhanced potency in the presence of heparin. Furthermore, it forms a protease-inhibiting heterodimer with TMPRSS7. Antithrombin III/Serpin C1 Protein, Human (HEK293, C-His) is the recombinant human-derived Antithrombin III/Serpin C1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of Antithrombin III/Serpin C1 Protein, Human (HEK293, C-His) is 430 a.a., with molecular weight of 55-60 kDa.
  • HY-P71077
    Serpin E1 Protein, Human (HEK293, His)

    Plasminogen Activator Inhibitor 1; PAI; PAI-1; Endothelial Plasminogen Activator Inhibitor; serpin E1; serpinE1; PAI1; PLANH1

    		 Human HEK293
    Serpin E1 is a serine protease inhibitor that regulates various cellular processes by inhibiting TMPRSS7, tissue-type plasminogen activator (PLAT), and urokinase-type plasminogen activator (PLAU). During fibrinolysis, it downregulates PLAT to control thrombus degradation and acts as a PLAU inhibitor to regulate cell adhesion. Serpin E1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin E1 Protein, Human (HEK293, His) is 379 a.a., with molecular weight of ~44-51 kDa.
  • HY-P71303
    Serpin B1 Protein, Human (HEK293, His)

    Leukocyte elastase inhibitor; serpinB1; Monocyte/neutrophil elastase inhibitor; M/NEI; Peptidase inhibitor 2; PI-2

    		 Human HEK293
    Serpin B1 protein is an important neutrophil serine protease inhibitor that regulates innate immune responses by protecting cells from cytoplasmic proteases during stress. It inhibits various neutrophil proteases, including elastase and chymotrypsin, and blocks GZMH activity intracellularly. Serpin B1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B1 Protein, Human (HEK293, His) is 379 a.a., with molecular weight of ~44.0 kDa.
  • HY-P7542
    Serpin A1 Protein, Human (HEK293, His)

    rHuserpin A1/alpha-1-Antitrypsin, His; Alpha-1-Antitrypsin; Alpha-1 Protease Inhibitor; Alpha-1-Antiproteinase; serpin A1; serpinA1; AAT; PI

    		 Human HEK293
    Serpin A1 Protein, Human (HEK293, His) produced in HEK293 cells is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Alpha-1 Antitrypsin Exerts a hepatoprotective effect on immune-mediated hepatitis and acetaminophen-induced liver injury.
  • HY-P70498
    Serpin F1 Protein, Human (HEK293, His)

    Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 protein; EPC-1; serpin F1; serpinF1; PEDF

    		 Human HEK293
    Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin F1 Protein, Human (HEK293, His) is 399 a.a., with molecular weight of ~50.0 kDa.
  • HY-P71054
    Serpin A3 Protein, Human (K267R, HEK293, His)

    Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 protein; serpin A3; serpinA3; AACT

    		 Human HEK293
    Serpin A3 Proteinas, with unclear physiological function, inhibits neutrophil cathepsin G and mast cell chymase, involved in angiotensin-1 to angiotensin-2 conversion. Serpin A3 also interacts with DNAJC1. Serpin A3 Protein, Human (K267R, HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-6*His labeled tag and K267R mutation. The total length of Serpin A3 Protein, Human (K267R, HEK293, His) is 400 a.a., with molecular weight of 56-80 kDa.
  • HY-P71292
    Serpin A10 Protein, Human (HEK293, His)

    protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; serpin A10; serpinA10; ZPI

    		 Human HEK293
    Serpin A10 protein inhibits coagulation proteases, such as factor Xa, in the presence of PROZ, calcium, and phospholipids. It can also inhibit factor XIa without cofactors. Serpin A10 interacts with PROZ to exert its inhibitory effects on these coagulation factors. Serpin A10 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A10 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A10 Protein, Human (HEK293, His) is 423 a.a., with molecular weight of 55-80 kDa.
  • HY-P70498A
    Serpin F1 Protein, Human (HEK293, N-His)

    Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 protein; EPC-1; serpin F1; serpinF1; PEDF

    		 Human HEK293
    Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, N-His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of Serpin F1 Protein, Human (HEK293, N-His) is 399 a.a., with molecular weight of ~49.37 kDa.
  • HY-P71039
    Serpin I2 Protein, Human (HEK293, His)

    serpinI2; serpin I2; Myoepithelium-derived serine protease inhibitor; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14; MEPI; PI14;

    		Human HEK293
    Serpin I2 Protein, is a member of the serpin (serine protease inhibitor) superfamily. Serpin I2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin. Serpin I2 is downregulated in pancreatic and breast cancer, and associated with acinar cell apoptosis and pancreatic insufficiency when absent in mice. Serpin I2 is associated with refractive error and has the potential for further investigations of the genetic susceptibility to myopia research. Serpin I2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin I2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin I2 Protein, Human (HEK293, His) is 387 a.a., with molecular weight of 44-60 kDa.
  • HY-P71085
    Serpin E2 Protein, Human (HEK293, His)

    Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; serpin E2; serpinE2; PI7; PN1

    		 Human HEK293
    Serpin E2 is a serine protease inhibitor that inhibits thrombin, trypsin, and urokinase. Its unique role in promoting neurite extension involves specific inhibition of thrombin activity. Serpin E2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin E2 Protein, Human (HEK293, His) is 378 a.a., with molecular weight of ~50.0 kDa.
  • HY-P70975
    Serpin A5 Protein, Human (HEK293, His)

    Plasma Serine Protease Inhibitor; Acrosomal Serine Protease Inhibitor; Plasminogen Activator Inhibitor 3; PAI-3; PAI3; protein C Inhibitor; PCI; serpin A5; serpinA5; PCI; PLANH3; PROCI

    		 Human HEK293
    Plasma serine protease inhibitor (SERPINA5) is a glycoproteins that inhibit serine proteases. SERPINA5 is involved in the regulation of intravascular and extravascular proteolytic activities, controls the sperm motility and fertilization and protect components of the genital tract. SERPINA5 also inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. Serpin A5 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A5 Protein, Human (HEK293, His) is 387 a.a., with molecular weight of 44-55 kDa.
  • HY-P71298
    Serpin H1 Protein, Human (HEK293, His)

    serpin H1; 47 kDa Heat Shock protein; Arsenic-Transactivated protein 3; AsTP3; Cell Proliferation-Inducing Gene 14 protein; Collagen-Binding protein; Colligin; Rheumatoid Arthritis-Related Antigen RA-A47; serpinH1; CBP1; CBP2; HSP47; serpinH2

    		 Human HEK293
    Serpin H1 protein exhibits a specific affinity for collagen, indicating its role as a chaperone in the biosynthetic pathway of collagen. This suggests its potential contribution to collagen synthesis, emphasizing its importance in maintaining tissue integrity and modulating cellular responses related to collagen metabolism. Serpin H1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin H1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin H1 Protein, Human (HEK293, His) is 400 a.a., with molecular weight of ~51.0 kDa.
  • HY-P71142
    Serpin B3 Protein, Human (HEK293, His)

    serpin B3; protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1

    		 Human HEK293
    The Serpin B3 protein exhibits versatility in cellular regulation and may act as a papain-like cysteine protease inhibitor to modulate immune responses against tumor cells. Its dual role extends to inhibiting UV-induced apoptosis by inhibiting c-Jun NH(2)-terminal kinase (JNK1) activity, suggesting that Serpin B3 is involved in the stress response. Serpin B3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B3 Protein, Human (HEK293, His) is 390 a.a., with molecular weight of 41-50 kDa.
  • HY-P7270
    Neuroserpin Protein, Human (CHO)

    rHuNeuroserpin; Peptidase inhibitor 12; serpin I1; serpinI1

    		 Human CHO
    Neuroserpin Protein, Human (CHO) is a member of the serpin family of serine protease inhibitors, playing an important role in synaptic plasticity and memory formation in the hippocampus.
  • HY-P71299
    Vaspin Protein, Human (GST)

    serpin A12; OL-64; Visceral Adipose Tissue-Derived Serine Protease Inhibitor; Vaspin; Visceral Adipose-Specific serpin; serpinA12

    		 Human E. coli
    Vaspin is an adipokine that regulates adipogenesis, metabolism, and inflammation by binding to the chemokine receptors CMKLR1 and CMKLR2. It mainly regulates adipocyte differentiation and affects lipid and glucose metabolism genes. Vaspin Protein, Human (GST) is the recombinant human-derived Vaspin protein, expressed by E. coli , with N-GST labeled tag. The total length of Vaspin Protein, Human (GST) is 394 a.a., with molecular weight of ~72.0 kDa.
  • HY-P71300
    Vaspin Protein, Human (HEK293, His)

    serpin A12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin; serpinA12

    		 Human HEK293
    Vaspin is an adipokine that regulates adipogenesis, metabolism, and inflammation by binding to the chemokine receptors CMKLR1 and CMKLR2. It mainly regulates adipocyte differentiation and affects lipid and glucose metabolism genes. Vaspin Protein, Human (HEK293, His) is the recombinant human-derived Vaspin protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Vaspin Protein, Human (HEK293, His) is 394 a.a., with molecular weight of 50-60 kDa.

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