TRAIL R2/TNFRSF10B Protein, Mouse (HEK 293, hFc)

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
2 μg	$83	In-stock	Estimated Time of Arrival: December 31
10 μg	$210	In-stock	Estimated Time of Arrival: December 31
50 μg	$570	In-stock	Estimated Time of Arrival: December 31
100 μg		Get quote
250 μg		Get quote

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TRAIL R2/TNFRSF10B Protein, Mouse (HEK 293, hFc) Featured Recommendations:

Biological Activity	The ED₅₀ as determined by its ability to inhibit TRAIL-mediated cytotoxicity using L929 mouse fibroblast cells treated with TRAIL is less than 1 μg/mL.
Species	Mouse
Source	HEK293
Tag	C-hFc
Accession	Q9QZM4 (N53-S177)
Gene ID	21933 [NCBI]
Synonyms	Tnfrsf10b; Dr5; Killer; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; MK; CD antigen CD262
AA Sequence	NPAHNRPAGLQRPEESPSRGPCLAGQYLSEGNCKPCREGIDYTSHSNHSLDSCILCTVCKEDKVVETRCNITTNTVCRCKPGTFEDKDSPEICQSCSNCTDGEEELTSCTPRENRKCVSKTAWAS
Molecular Weight	Approximately 50 kDa
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Appearance	Lyophilized powder.
Formulation	Lyophilized from a 0.2 μm solution of 20 mM PBS, 150 mM NaCl, pH 7.4.
Endotoxin Level	<1 EU/μg, determined by LAL method.
Reconstitution	It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.
Storage & Stability	Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Shipping	Room temperature in continental US;may vary elsewhere.
Documentation	Select Batch: Data Sheet (233 KB) SDS (251 KB) COA (220 KB) Handling Instructions (2659 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Specific Activity (Unit/mg) = 10⁶ ÷ Biological Activity (ED₅₀)

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