1. Recombinant Proteins
  2. Wnt3a Protein, Human (HEK293)

Wnt3a Protein, Human (HEK293)

Cat. No.: HY-P70453
Handling Instructions

Wnt3a Protein, Human (HEK293) is 100-120 kDa wnt3a protein expressed in HEK 293 system. Wnt3a specifically promotes Wnt/β-catenin signaling pathway by stabilization of intracellular beta-catenin levels[1].

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $140 In-stock
Estimated Time of Arrival: December 31
50 μg $420 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt3a; Wnt-3a
Species

Human

Source

HEK 293

Accession

P56704 (S19-K352)

Gene ID

89780

Molecular Weight

100-120 kDa

AA Sequence

SYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US;may vary elsewhere.

Background

Wnt-3a belongs to the Wnt family of proteins that consist of structurally related genes encoding highly conserved cysteine-rich secreted glycoproteins. Wnts are ligands for seven-pass transmembrane receptors of the frizzled family. Wnts bind Frizzled receptors and forms complex with lLRP5 or LRP6, which results in the stabilization of intracellular beta-catenin levels.
Wnt-3a is a 44 kDa secreted hydrophobic glycoprotein containing a conserved pattern of 24 cysteine residues.
Human Wnt-3a shares 96% amino acid (aa) identity with mouse, and bovineWnt-3a.
Wnt-3a, a novel Wnt protein, specifically promotes Wnt/β-catenin signaling pathway[1][2].

Documentation
References
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Product Name:
Wnt3a Protein, Human (HEK293)
Cat. No.:
HY-P70453
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